OpenAlex 1,437 works 34 author topics
Works
1,437 works
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YÖKSİS
SJR Q1
JCR Q2
OpenAlex top 1%
OpenAlex 99.1%
No abstract yet.
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OpenAlex top 1%
OpenAlex 99.7%
Oxidative stress may play a crucial role in age-related neurodegenerative disorders. Here, we examined the ability of two antioxidants, alpha-lipoic acid (LA) and N-acetylcysteine (NAC), to reverse the cognitive deficits found in the SAMP8 mouse. By 12 months of age, this strain develops elevated levels of Abeta and s…
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SJR Q1
OpenAlex top 1%
OpenAlex 99.9%
α-lipoic acid (ALA, thioctic acid) is an organosulfur component produced from plants, animals, and humans. It has various properties, among them great antioxidant potential and is widely used as a racemic drug for diabetic polyneuropathy-associated pain and paresthesia. Naturally, ALA is located in mitochondria, where…
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YÖKSİS
SJR Q1
JCR Q2
OpenAlex top 1%
OpenAlex 99.9%
α-lipoic acid (ALA, thioctic acid) is an organosulfur component produced from plants, animals, and humans. It has various properties, among them great antioxidant potential and is widely used as a racemic drug for diabetic polyneuropathy-associated pain and paresthesia. Naturally, ALA is located in mitochondria, where…
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YÖKSİS
SJR Q1
JCR Q2
OpenAlex top 1%
OpenAlex 99.9%
α-lipoic acid (ALA, thioctic acid) is an organosulfur component produced from plants, animals, and humans. It has various properties, among them great antioxidant potential and is widely used as a racemic drug for diabetic polyneuropathy-associated pain and paresthesia. Naturally, ALA is located in mitochondria, where…
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YÖKSİS
SJR Q1
JCR Q2
OpenAlex top 1%
OpenAlex 99.9%
α-lipoic acid (ALA, thioctic acid) is an organosulfur component produced from plants, animals, and humans. It has various properties, among them great antioxidant potential and is widely used as a racemic drug for diabetic polyneuropathy-associated pain and paresthesia. Naturally, ALA is located in mitochondria, where…
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YÖKSİS
SJR Q1
JCR Q1
OpenAlex top 1%
OpenAlex 99.3%
Steroid-resistant nephrotic syndrome (SRNS) is a frequent cause of end-stage renal failure. Identification of single-gene causes of SRNS has generated some insights into its pathogenesis; however, additional genes and disease mechanisms remain obscure, and SRNS continues to be treatment refractory. Here we have identi…
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YÖKSİS
SJR Q1
JCR Q1
OpenAlex top 1%
OpenAlex 99.3%
Steroid-resistant nephrotic syndrome (SRNS) is a frequent cause of end-stage renal failure. Identification of single-gene causes of SRNS has generated some insights into its pathogenesis; however, additional genes and disease mechanisms remain obscure, and SRNS continues to be treatment refractory. Here we have identi…
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ADCK4 mutations promote steroid resistant nephrotic syndrome through CoQ10 biosynthesis disruption 2013YÖKSİS SJR Q1 JCR Q1 OpenAlex top 10% OpenAlex 98.9%
Identification of single-gene causes of steroid-resistant nephrotic syndrome (SRNS) has furthered the understanding of the pathogenesis of this disease. Here, using a combination of homozygosity mapping and whole human exome resequencing, we identified mutations in the aarF domain containing kinase 4 (ADCK4) gene in 1…
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YÖKSİS
SJR Q1
JCR Q2
OpenAlex top 10%
OpenAlex 93.7%
BACKGROUND: Mitochondria are the main production site of free oxygen radicals, which can cause organ dysfunction by oxidation of cellular macromolecules such as carbohydrates, lipids and proteins. Oxidative stress may result from either overproduction of these species or from failure of the antioxidant defence systems…
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YÖKSİS
SJR Q1
JCR Q3
OpenAlex top 10%
OpenAlex 93.7%
BACKGROUND: Mitochondria are the main production site of free oxygen radicals, which can cause organ dysfunction by oxidation of cellular macromolecules such as carbohydrates, lipids and proteins. Oxidative stress may result from either overproduction of these species or from failure of the antioxidant defence systems…
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YÖKSİS
SJR Q1
JCR Q1
OpenAlex top 1%
OpenAlex 99.6%
No abstract yet.
Academicians
34 academicians
- EMRE SARANDÖL 16 author topics
- OKTAY ARSLAN 14 author topics
- TAHA ABDULKADİR ÇOBAN 8 author topics
- EMİNE DIRAMAN 7 author topics
- MESUT BÜNYAMİ HALICI 7 author topics
- RABİYE TERZİ 7 author topics
- DİLEK BAYRAM 6 author topics
- ELİF ERDEM GÜZEL 6 author topics
- FATMA NİHAN CANKARA 6 author topics
- AYŞE KOÇAK SEZGİN 5 author topics
- ÇETİN PEKÇETİN 5 author topics
- ERAY ÖZGÜN 5 author topics