Takotsubo Cardiomyopathy and Associated Phenomena

BACKGROUND AND PURPOSE: Stroke has been shown to alter autonomic function. The purpose of this study was to show the differential effects of stroke localization on autonomic function parameters assessed by heart rate variability (HRV). METHODS: To determine the differential effect of ischemic stroke localization on au…

• MEHMET AKİF TOPÇUOĞLU

BACKGROUND: Myocardial injury can occur after ischemic stroke in the absence of primary cardiac causes. The neuroanatomic basis of stroke-related myocardial injury is not well understood. OBJECTIVE: To identify regions of brain infarction associated with myocardial injury using a method free of the bias of an a priori…

• ETHEM MURAT ARSAVA

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OBJECTIVE: To determine the relationship between blood glucose levels (mg/dL) and occurrence of symptomatic vasospasm (VSP) and clinical outcomes after aneurysmal subarachnoid hemorrhage. DESIGN: Retrospective observational study of 352 patients with subarachnoid hemorrhage admitted within 48 hrs of ictus between Janu…

• MEHMET AKİF TOPÇUOĞLU

INTRODUCTION: QT dispersion (QTd, range of QT intervals in 12 ECG leads) is thought to reflect spatial heterogeneity of ventricular refractoriness. However, QTd may be largely due to projections of the repolarization dipole rather than "nondipolar" signals. METHODS AND RESULTS: Seventy-eight normal subjects (47+/-16 y…

• BURAK ACAR

The pathogenesis of high-altitude pulmonary oedema (HAPE) is disputed. Recent reports show a strong correlation between the occurrence of HAPE and pulmonary artery pressure, and it is known that the oedema is of the high-permeability type. We have, therefore, proposed that HAPE is caused by ultrastructural damage to p…

• SANLI SADİ KURDAK

OBJECT: The aim of this study was to assess the diagnostic yield of imaging tests performed in patients in whom the cause of subarachnoid hemorrhage (SAH) had not been demonstrated on initial angiography. METHODS: By reviewing medical records of 806 patients with SAH who had been admitted during a 6.5-year period, the…

• MEHMET AKİF TOPÇUOĞLU

BACKGROUND: There is substantial evidence to suggest that oxidative stress plays a significant role in the development of acute brain injury after subarachnoid hemorrhage (SAH). OBJECTIVE: To investigate the putative neuroprotective effect of nesfatin-1, a novel peptide with anorexigenic properties, in a rat model of…

• AZİZE ŞENER

Acute coronary syndrome is a precipitant of acute heart failure in a substantial proportion of cases, and the presence of both conditions is associated with a higher risk of short-term mortality compared to acute coronary syndrome alone. The diagnosis of acute coronary syndrome in the setting of acute heart failure ca…

• MEHMET BİRHAN YILMAZ

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• TEYYAR GÖKDENİZ

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• İBRAHİM HALİL TANBOĞA