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OpenAlex topic

HIV/AIDS drug development and treatment

This page lists works and academicians tagged with an OpenAlex topic. It is not a YÖKSİS primary or secondary field.

OpenAlex 894 works 30 author topics

Works

894 works

  1. 96 weeks treatment of tenofovir alafenamide vs. tenofovir disoproxil fumarate for hepatitis B virus infection 2018
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 1% OpenAlex 99.8%

    No abstract yet.

  2. 96 weeks treatment of tenofovir alafenamide vs. tenofovir disoproxil fumarate for hepatitis B virus infection 2018
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 1% OpenAlex 99.8%

    No abstract yet.

  3. ABT 450 Ritonavir Ombitasvir and Dasabuvir Achieves 97 and 100 Sustained Virologic Response With or Without Ribavirin in Treatment Experienced Patients With HCV Genotype 1b Infection 2014
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 1% OpenAlex 99.8%

    BACKGROUND & AIMS: The interferon-free regimen of ABT-450 (a protease inhibitor), ritonavir, ombitasvir (an NS5A inhibitor), dasabuvir (a non-nucleoside polymerase inhibitor), and ribavirin has shown efficacy in patients with hepatitis C virus (HCV) genotype 1b infection-the most prevalent subgenotype worldwide. We ev…

  4. Oral prenylation inhibition with lonafarnib in chronic hepatitis D infection: a proof-of-concept randomised, double-blind, placebo-controlled phase 2A trial 2015
    OpenAlex top 1% OpenAlex 99.3%

    No abstract yet.

  5. Intrinsic and Acquired Resistance to Methotrexate in Acute Leukemia 1996
    OpenAlex top 1% OpenAlex 99.3%

    Methotrexate, a folic acid antagonist, is used extensively not only for the treatment of cancer but also for the treatment of rheumatoid arthritis, psoriasis, and autoimmune disease and for the prevention of graft-versus-host disease after transplantation. The drug is also used as an abortifacient.1,2 Other folate ant…

  6. Synthesis of some novel thiourea derivatives obtained from 5 4 aminophenoxy methyl 4 alkyl aryl 2 4 dihydro 3H 1 2 4 triazole 3 thiones and evaluation as antiviral anti HIV and anti tuberculosis agents 2008
    YÖKSİS SJR Q1 JCR Q2 OpenAlex top 10% OpenAlex 92.5%

    No abstract yet.

  7. Synthesis of some novel thiourea derivatives obtained from 5 4 aminophenoxy methyl 4 alkyl aryl 2 4 dihydro 3H 1 2 4 triazole 3 thiones and evaluation as antiviral anti HIV and anti tuberculosis agents 2008
    YÖKSİS SJR Q1 JCR Q2 OpenAlex top 10% OpenAlex 92.5%

    No abstract yet.

  8. The Molecular Basis of Drug Resistance against Hepatitis C Virus NS3/4A Protease Inhibitors 2012
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 10% OpenAlex 98.9%

    Hepatitis C virus (HCV) infects over 170 million people worldwide and is the leading cause of chronic liver diseases, including cirrhosis, liver failure, and liver cancer. Available antiviral therapies cause severe side effects and are effective only for a subset of patients, though treatment outcomes have recently be…

  9. Mechanisms for the Negative Effects of Internalized HIV-Related Stigma on Antiretroviral Therapy Adherence in Women 2016
    OpenAlex top 1% OpenAlex 99.3%

    BACKGROUND: Internalization of HIV-related stigma may inhibit a person's ability to manage HIV disease through adherence to treatment regimens. Studies, mainly with white men, have suggested an association between internalized stigma and suboptimal adherence to antiretroviral therapy (ART). However, there is a scarcit…

  10. Multimode, Cooperative Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors 2012
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 1% OpenAlex 99.1%

    The multifunctional HIV-1 enzyme integrase interacts with viral DNA and its key cellular cofactor LEDGF to effectively integrate the reverse transcript into a host cell chromosome. These interactions are crucial for HIV-1 replication and present attractive targets for antiviral therapy. Recently, 2-(quinolin-3-yl) ace…

  11. Entecavir therapy for lamivudine refractory chronic hepatitis B Improved virologic biochemical and serology outcomes through 96 weeks 2008
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 1% OpenAlex 99.5%

    UNLABELLED: In hepatitis B e antigen (HBeAg)-positive chronic hepatitis B patients who were refractory to current lamivudine therapy, switching to entecavir was superior to continued lamivudine at week 48 for histologic improvement, viral load reduction by polymerase chain reaction and alanine aminotransferase normali…

  12. A trimethoprim derivative impedes antibiotic resistance evolution 2021
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 10% OpenAlex 98.4%

    The antibiotic trimethoprim (TMP) is used to treat a variety of Escherichia coli infections, but its efficacy is limited by the rapid emergence of TMP-resistant bacteria. Previous laboratory evolution experiments have identified resistance-conferring mutations in the gene encoding the TMP target, bacterial dihydrofola…

Academicians

30 academicians