OpenAlex 3,050 works 96 author topics
Works
3,050 works
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The pathogenesis of periodontitis involves a complex immune/inflammatory cascade that is initiated by the bacteria of the oral biofilm that forms naturally on the teeth. The susceptibility to periodontitis appears to be determined by the host response; specifically, the magnitude of the inflammatory response and the d…
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Human neutrophils constitutively undergo apoptosis and this process is critical for the resolution of inflammation. Whilst neutrophil apoptosis can be modulated by a wide variety of agents including GM-CSF, LPS and TNF-alpha, the molecular mechanisms underlying neutrophil death and survival remain largely undefined. R…
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X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19 2021YÖKSİS SJR Q1 JCR Q1 OpenAlex top 1% OpenAlex 100.0%
The patients' blood plasmacytoid dendritic cells (pDCs) produce low levels of type I IFNs in response to SARS-CoV-2. Overall, X-linked recessive TLR7 deficiency is a highly penetrant genetic etiology of critical COVID-19 pneumonia, in about 1.8% of male patients below the age of 60 years. Human TLR7 and pDCs are essen…
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Toll-like receptor 2 (TLR2), a member of the Toll-like receptor family, plays an important role in recognition of, and subsequent immune response activation against, mycobacteria. The genetic polymorphism of TLR2 (arginine to glutamine substitution at residue 753 (Arg753Gln)) has been associated with a negative influe…
Academicians
96 academicians
- AYŞE ER 16 author topics
- ZEKAİ HALICI 16 author topics
- ENVER YAZAR 15 author topics
- ALPER BEKTAŞ İSKİT 14 author topics
- MUAMMER ELMAS 12 author topics
- ASUMAN DEVECİ ÖZKAN 11 author topics
- EROL ERDURAN 11 author topics
- EYÜP SABRİ AKARSU 9 author topics
- BANU BAYYURT KOCABAŞ 8 author topics
- ELİF ÇADIRCI 8 author topics
- EVREN ŞENTÜRK 8 author topics
- BÜNYAMİN TRAŞ 7 author topics