OpenAlex 1,193 works 53 author topics
Works
1,193 works
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YÖKSİS
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OpenAlex top 1%
OpenAlex 99.9%
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Impairment of BRCA1 Related DNA Double Strand Break Repair Leads to Ovarian Aging in Mice and Humans 2013YÖKSİS SJR Q1 JCR Q1 OpenAlex top 1% OpenAlex 99.5%
The underlying mechanism behind age-induced wastage of the human ovarian follicle reserve is unknown. We identify impaired ATM (ataxia-telangiectasia mutated)-mediated DNA double-strand break (DSB) repair as a cause of aging in mouse and human oocytes. We show that DSBs accumulate in primordial follicles with age. In…
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OpenAlex top 1%
OpenAlex 99.1%
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OpenAlex 99.3%
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YÖKSİS
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OpenAlex 99.3%
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OpenAlex 89.4%
The relationship between dNTP levels and DNA synthesis was investigated using alpha factor-synchronized yeast treated with the ribonucleotide reductase inhibitor hydroxyurea (HU). Although HU blocked DNA synthesis and prevented the dNTP pool expansion that normally occurs at G1/S, it did not exhaust the levels of any…
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YÖKSİS
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OpenAlex top 10%
OpenAlex 96.8%
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YÖKSİS
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OpenAlex 94.7%
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YÖKSİS
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OpenAlex top 10%
OpenAlex 97.9%
No abstract yet.
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OpenAlex top 10%
OpenAlex 98.8%
No abstract yet.
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YÖKSİS
SJR Q1
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OpenAlex top 10%
OpenAlex 97.5%
No abstract yet.
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YÖKSİS
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OpenAlex top 10%
OpenAlex 98.5%
The platinum-based drug cisplatin is a widely used first-line therapy for several cancers. Cisplatin interacts with DNA mainly in the form of Pt-d(GpG) di-adduct, which stalls cell proliferation and activates DNA damage response. Although cisplatin shows a broad spectrum of anticancer activity, its utility is limited…
Academicians
53 academicians
- OGÜN ADEBALİ 34 author topics
- BENSU KARAHALİL 25 author topics
- ERDEM COŞKUN 24 author topics
- MEHMET GÜVEN 24 author topics
- MELTEM MÜFTÜOĞLU 24 author topics
- ALEX LYAKHOVICH 22 author topics
- BAHADIR BATAR 21 author topics
- CEMALETTİN BEKPEN 13 author topics
- GAMZE GÜNEY ESKİLER 11 author topics
- AYŞE BAŞAK ENGİN 10 author topics
- BEDİA ÇAKMAKOĞLU 10 author topics
- SEMRA ŞARDAŞ 10 author topics