OpenAlex 1,907 works 100 author topics
Works
1,907 works
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YÖKSİS
SJR Q2
JCR Q2
OpenAlex top 1%
OpenAlex 99.7%
Quercetin is a flavonoid with notable pharmacological effects and promising therapeutic potential. It is widely distributed among plants and found commonly in daily diets predominantly in fruits and vegetables. Neuroprotection by quercetin has been reported in several in vitro studies. It has been shown to protect neu…
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OpenAlex top 1%
OpenAlex 99.7%
Oxidative stress may play a crucial role in age-related neurodegenerative disorders. Here, we examined the ability of two antioxidants, alpha-lipoic acid (LA) and N-acetylcysteine (NAC), to reverse the cognitive deficits found in the SAMP8 mouse. By 12 months of age, this strain develops elevated levels of Abeta and s…
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OpenAlex top 1%
OpenAlex 99.1%
Alzheimer's disease (AD) is a highly complex neurodegenerative disorder of the aged that has multiple factors which contribute to its etiology in terms of initiation and progression. This review summarizes these diverse aspects of this form of dementia. Several hypotheses, often with overlapping features, have been fo…
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YÖKSİS
OpenAlex top 1%
OpenAlex 99.3%
BACKGROUND: The identification of early mechanisms underlying Alzheimer's Disease (AD) and associated biomarkers could advance development of new therapies and improve monitoring and predicting of AD progression. Mitochondrial dysfunction has been suggested to underlie AD pathophysiology, however, no comprehensive stu…
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YÖKSİS
SJR Q1
JCR Q2
OpenAlex top 1%
OpenAlex 99.4%
No abstract yet.
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YÖKSİS
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OpenAlex top 1%
OpenAlex 99.3%
No abstract yet.
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YÖKSİS
SJR Q2
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OpenAlex top 1%
OpenAlex 99.4%
No abstract yet.
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YÖKSİS
SJR Q2
JCR Q3
OpenAlex top 1%
OpenAlex 99.4%
No abstract yet.
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YÖKSİS
SJR Q2
JCR Q3
OpenAlex top 10%
OpenAlex 98.2%
The characteristic features of Alzheimer's disease (AD) are the appearance of extracellular amyloid-beta (Aβ) plaques and neurofibrillary tangles in the intracellular environment, neuronal death and the loss of synapses, all of which contribute to cognitive decline in a progressive manner. A number of hypotheses have…
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YÖKSİS
SJR Q1
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OpenAlex top 10%
OpenAlex 99.0%
No abstract yet.
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YÖKSİS
SJR Q2
JCR Q3
OpenAlex top 1%
OpenAlex 99.3%
No abstract yet.
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YÖKSİS
SJR Q1
JCR Q1
OpenAlex top 10%
OpenAlex 98.7%
α-Synuclein misfolding and aggregation is a hallmark in Parkinson's disease and in several other neurodegenerative diseases known as synucleinopathies. The toxic properties of α-synuclein are conserved from yeast to man, but the precise underpinnings of the cellular pathologies associated are still elusive, complicati…
Academicians
100 academicians
- ERDİNÇ DURSUN 44 author topics
- DUYGU GEZEN AK 40 author topics
- BAŞAR BİLGİÇ 29 author topics
- ORKİDE COŞKUNER WEBER 21 author topics
- SELMA YILMAZER 21 author topics
- AHMET TARIK BAYKAL 12 author topics
- BURAK YULUĞ 12 author topics
- ŞEYDA ÇANKAYA 10 author topics
- MEHMET ENES ARSLAN 9 author topics
- AYLA ÖZTÜRK 8 author topics
- MUHAMMET EMİN ÇAM 8 author topics
- NİLGÜN ÇINAR 8 author topics