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Article detail · 2016

Antibacterial effects of curcumin: An in vitro minimum inhibitory concentration study

Journal

Toxicology and Industrial Health

ISSN 0748-2337

YÖKSİS OpenAlex SJR Q2 JCR Q3 Citations 273 Percentile 80.1% FWCI 1.51
Year
2016
DOI
10.1177/0748233713498458
Type
article

Data source split

  • YÖKSİS YÖKSİS article record
  • YÖKSİS venue TOXICOLOGY AND INDUSTRIAL HEALTH
  • Catalog match (ISSN) Toxicology and Industrial Health
  • OpenAlex OpenAlex enrichment (abstract, citations, topics)

OpenAlex record

Abstract

OpenAlex · English

AIM: To evaluate the antibacterial effect of curcumin with the minimum inhibitory concentration (MIC) method in standard bacterial strains. METHODS: The in vitro antibacterial activity of curcumin was evaluated against methicillin-sensitive Staphylococcus aureus (MSSA) (ATCC 29213), methicillin-resistant Staphylococcus aureus (MRSA) (ATCC 43300), Enterococcus faecalis (ATCC 29212), Bacillus subtilis (ATCC 6633), Pseudomonas aeruginosa (ATCC 27853), Escherichia coli (ATCC 25922) and Klebsiella pneumoniae (ATCC 700603) using the macrodilution broth susceptibility test method. After incubation in tubes, the antibacterial activity of curcumin was detected by a lack of turbidity, which indicated the inhibition of bacterial growth. The concentration in the tube with the highest dilution showing no turbidity was defined as the MIC. RESULTS: The curcumin MIC values were 175 µg/ml, 129 µg/ml, 219 µg/ml, 217 µg/ml, 163 µg/ml, 293 µg/ml and 216 µg/ml against P. aeruginosa, B. subtilis, MSSA, MRSA, E. coli, E. faecalis and K. Pneumonia, respectively. CONCLUSION: This study revealed antibacterial effects of curcumin against standard bacterial strains in high concentrations. Animal experiments have demonstrated that curcumin applied at high doses has strong antibacterial activity. There is a need for further in vivo studies to shed light on antibacterial effects of curcumin with high concentrations.

Topics

Citations

OpenAlex cited_by_count. Not a WoS or Scopus citation count; those sources have no separate column here.

273 citations

OpenAlex cited_by_count (cache / database)

22 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).

  1. Biological Activities of Citrus limon L. and Citrus sinensis L. Peel Essential Oils 2022 Citations 39 · OpenAlex
  2. Biological Activities of Citrus limon L. and Citrus sinensis L. Peel Essential Oils 2022 Citations 39 · OpenAlex
  3. Curcumin-loaded silk fibroin e-gel scaffolds for wound healing applications 2018 Citations 36 · OpenAlex
  4. Tuning stimuli-responsive properties of alginate hydrogels through layer-by-layer functionalization for dual-responsive dual drug release 2023 Citations 32 · OpenAlex
  5. Tuning stimuli-responsive properties of alginate hydrogels through layer-by-layer functionalization for dual-responsive dual drug release 2023 Citations 32 · OpenAlex
  6. Curcumin nanoparticles supported gelatin-collagen scaffold: Preparation, characterization, and in vitro study 2021 Citations 14 · OpenAlex
  7. Curcumin nanoparticles supported gelatin-collagen scaffold: Preparation, characterization, and in vitro study 2021 Citations 14 · OpenAlex
  8. Curcumin-meropenem synergy in carbapenem resistant Klebsiella pneumoniae curcumin-meropenem synergy 2021 Citations 12 · OpenAlex
  9. Determination of Potential Antimicrobial Activities of some Local Berries Fruits in Kombucha Tea Production 2021 Citations 12 · OpenAlex
  10. Curcumin-meropenem synergy in carbapenem resistant Klebsiella pneumoniae curcumin-meropenem synergy 2021 Citations 12 · OpenAlex

Authors

  1. ABDULLAH GÜMÜŞ KAFKAS ÜNİVERSİTESİ