OpenAlex 317 works 7 author topics
Works
317 works
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YÖKSİS
SJR Q1
JCR Q1
OpenAlex top 10%
OpenAlex 92.7%
In the recently identified cholesterol catabolic pathway of Mycobacterium tuberculosis, 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (HsaD) is proposed to catalyze the hydrolysis of a carbon-carbon bond in 4,5-9,10-diseco-3-hydroxy-5,9,17-tri-oxoandrosta-1(10),2-diene-4-oic acid (DSHA), the cholesterol meta-cle…
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OpenAlex top 10%
OpenAlex 94.8%
Abstract An increasing number of synthetic vitamin D analogues (deltanoids) are now being used as sensitive molecular biology probes and also as new drug candidates and new drugs for treatment of various human diseases. The design and stereocontrolled synthesis of such new deltanoids are guided by considering cataboli…
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OpenAlex top 10%
OpenAlex 95.7%
When alpha-hydroxytamoxifen (alpha-OHTAM) was incubated with rat liver hydroxysteroid (alcohol) sulfotransferase a (STa) and 3'-phosphoadenosine 5'-phosphosulfate, (E)-alpha-OHTAM was found to be a better substrate for STa than (Z)-alpha-OHTAM. To explore the formation of tamoxifen (TAM)-derived DNA adducts, DNA was i…
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YÖKSİS
SJR Q1
JCR Q2
OpenAlex top 10%
OpenAlex 95.2%
No abstract yet.
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YÖKSİS
SJR Q2
JCR Q2
OpenAlex top 10%
OpenAlex 93.3%
Terpene derivatives converted by microbial biotransformation constitute an important resource for natural pharmaceutical, fragrance, and aroma substances. In the present study, the monoterpene α-phellandrene was biotransformed by 16 different strains of microorganisms (bacteria, fungi, and yeasts). The transformation…
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OpenAlex top 10%
OpenAlex 95.7%
No abstract yet.
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YÖKSİS
SJR Q2
JCR Q3
OpenAlex 79.4%
No abstract yet.
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YÖKSİS
SJR Q2
JCR Q3
OpenAlex 79.4%
No abstract yet.
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OpenAlex 78.0%
Bacterial degradation of steroids is widespread, but the metabolic pathways have rarely been explored. Previous studies with Pseudomonas sp. strain Chol1 and the C(24) steroid cholate have shown that cholate degradation proceeds via oxidation of the A ring, followed by cleavage of the C(5) acyl side chain attached to…
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OpenAlex 60.9%
No abstract yet.
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YÖKSİS
SJR Q1
JCR Q1
OpenAlex 78.6%
In Mycobacterium tuberculosis, the genes hsaD (2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolase) and nat (arylamine N-acetyltransferase) are essential for survival inside of host macrophages. These genes act as an operon and have been suggested to be involved in cholesterol metabolism. However, the role of NAT…
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YÖKSİS
SJR Q1
JCR Q1
OpenAlex 67.0%
No abstract yet.
Academicians
7 academicians