Biochemical and Structural Characterization

The rapid increase in drug-resistant infections has presented a serious challenge to antimicrobial therapies. The failure of the most potent antibiotics to kill "superbugs" emphasizes the urgent need to develop other control agents. Here we review the history and new development of antimicrobial peptides (AMPs), a gro…

• ALİ ADEM BAHAR

Peptidomimetics represent an important field in chemistry, pharmacology and material science as they circumvent the limitations of traditional peptides used in therapy. Self-structural organizations such as turns, helices, sheets and loops can be accessed by chemical modifications of amino acids or peptides. In-depth…

• İLKER AVAN

Özet henüz yok.

• IŞIN NERGİZ GEREN

Özet henüz yok.

• IŞIN NERGİZ GEREN

Özet henüz yok.

• KARLO MURATOĞLU

Özet henüz yok.

• ALİ AYDIN

Cyclotides are plant peptides comprising a circular backbone and three conserved disulfide bonds that confer them with exceptional stability. They were originally discovered in Oldenlandia affinis based on their use in traditional African medicine to accelerate labor. Recently, cyclotides have been identified in numer…

• MUHARREM AKCAN

Multiple sclerosis (MS) is the most common autoimmune disease affecting the central nervous system. It is characterized by auto-reactive T cells that induce demyelination and neuronal degradation. Treatment options are still limited and several MS medications need to be administered by parenteral application but are m…

Özet henüz yok.

• IŞIN NERGİZ GEREN

Özet henüz yok.

• IŞIN NERGİZ GEREN

There are many human oral antimicrobial peptides responsible for playing important roles including maintenance, repairing of oral tissues (hard or soft) and defense against oral microbes. In this review we have highlighted the biochemistry, physiology and proteomics of human oral histatin peptides, secreted from parot…

• ZOHAİB KHURSHID

Özet henüz yok.

• OĞUZ BAYRAKTAR