Animal testing and alternatives

Cell viability is defined as the number of healthy cells in a sample and proliferation of cells is a vital indicator for understanding the mechanisms in action of certain genes, proteins and pathways involved cell survival or death after exposing to toxic agents. Generally, methods used to determine viability are also…

• AYSUN ADAN

Cytotoxicity is one of the most important indicators for biological evaluation in vitro studies. In vitro, chemicals such as drugs and pesticides have different cytotoxicity mechanisms such as destruction of cell membranes, prevention of protein synthesis, irreversible binding to receptors etc. In order to determine t…

Snakebite has been considered as a burning and difficult situation not only for the affected individuals but also for the doctors.An individual, seeing the snake feels terrified.When there is bite by a snake one feels that the life is in danger now and death is unavoidable.This is, as evidence say, the main cause of d…

• EMİNE DIRAMAN

Snakebite has been considered as a burning and difficult situation not only for the affected individuals but also for the doctors.An individual, seeing the snake feels terrified.When there is bite by a snake one feels that the life is in danger now and death is unavoidable.This is, as evidence say, the main cause of d…

• MUHAMMET ALİ TUNÇ

Snakebite has been considered as a burning and difficult situation not only for the affected individuals but also for the doctors. An individual, seeing the snake feels terrified. When there is bite by a snake one feels that the life is in danger now and death is unavoidable. This is, as evidence say, the main cause o…

• HÜSEYİN FATİH GÜL

Snakebite has been considered as a burning and difficult situation not only for the affected individuals but also for the doctors. An individual, seeing the snake feels terrified. When there is bite by a snake one feels that the life is in danger now and death is unavoidable. This is, as evidence say, the main cause o…

• HÜSEYİN ERDOĞAN

OBJECTIVES: To develop a risk of bias tool for pre-clinical dental materials research studies that aims to support reporting of future investigations and improve assessment in systematic reviews. METHODS: A four-stage process following EQUATOR network recommendations was followed, which included project launch, litera…

• LEZİZE ŞEBNEM TÜRKÜN

INTRODUCTION: Genotoxicity and mutagenicity analyses have a significant role in the identification of hazard effects of therapeutic drugs, cosmetics, agrochemicals, industrial compounds, food additives, natural toxins and nanomaterials for regulatory purposes. To evaluate mutagenicity or genotoxicity, different in vit…

• HASAN TÜRKEZ
• ÖZLEM ÖZDEMİR TOZLU

INTRODUCTION: Genotoxicity and mutagenicity analyses have a significant role in the identification of hazard effects of therapeutic drugs, cosmetics, agrochemicals, industrial compounds, food additives, natural toxins and nanomaterials for regulatory purposes. To evaluate mutagenicity or genotoxicity, different in vit…

• HASAN TÜRKEZ
• MEHMET ENES ARSLAN

No abstract yet.

BACKGROUND: One of the major goals of oncology is to predict the response of patients with cancer to chemotherapeutic agents by employing laboratory methods variously called 'tumor chemosensitivity assays', 'drug response assays', or 'drug sensitivity assays', in vitro. The MTT assay is one of the methods used to pred…

• ENGİN ULUKAYA

BACKGROUND: One of the major goals of oncology is to predict the response of patients with cancer to chemotherapeutic agents by employing laboratory methods variously called 'tumor chemosensitivity assays', 'drug response assays', or 'drug sensitivity assays', in vitro. The MTT assay is one of the methods used to pred…

• MUKADDES ÇOLAKOĞULLARI