Pharmaceutical Quality and Counterfeiting

Objective: The pharmaceutical industry is constantly increasing in importance due to the ever-increasing need for health services, rising living standards, increasing average life expectancy, and advances in health technology. The approval of a new drug in the world varies from country to country. There may be differe…

rum (GAF), that provides a practical perspective on the treatment modality

Background In Ethiopia, veterinary pharmaceuticals and agricultural pesticides are vital to maintaining agricultural productivity and food security, yet their quality and safety regulation face significant challenges. Objectives This study aimed to assess the regulatory framework, institutional capacity, and routine q…

This mini-review examines the pharmaceutical industry’s shift from rigid, linear operating models toward agile business management. Drivers include personalised medicine, global health crises (e.g., pandemics), and increasing supply-chain complexity. We summarise how agile principles are applied across the value chain…

). Here, we exploit this dual functionality to track the potent nitrile-containing 5-lipoxygenase-activating protein (FLAP) antagonist BRP-685 in primary human macrophages using label-free spontaneous and stimulated Raman scattering. This approach enables direct intracellular localization at biologically relevant, low…

A rapid, simple, and cost-effective spectrophotometric method combined with multivariate chemometric calibration was developed for the simultaneous determination of paracetamol (PRC), caffeine (CFN), and propyphenazone (PRPN) in a ternary pharmaceutical formulation without any prior separation step. The direct UV spec…

• ERDAL DİNÇ

This study investigated the colour values (L*, a*, b*, C* and H°), pesticide residue (PR) levels, and chemical compound compositions of red pepper flakes, red pepper powder, and flakes of isot, a distinctive regional type of chilli pepper. PR levels and chemical component compositions of the spices were determined. Th…

Background/Objectives: Effective antimicrobial stewardship (AMS) is vital for containing antimicrobial resistance (AMR), yet evidence regarding existing regulatory frameworks in low- and middle-income countries (LMICs) remains scarce. This study conducted a landscape analysis of policies, laws, and regulations governi…

ABSTRACT New tadalafil analogues were found to be added illegally to an herbal supplement marketed for the enhancement of sexual function. The compounds were separated using flash column chromatography. The structures of the detected tadalafil analogues were elucidated by HPLC‐DAD/MS and nuclear magnetic resonance (NM…

• FATIMA DOĞANÇ

Fourier-transform infrared (FTIR) spectroscopy is widely used instrumental technique in pharmaceutical analysis. In this study, three pharmaceuitcal active ingredients representing different clinical and therapeutic classes (diflunisal, diltiazem and hydroxyzine) were investigated using regional spectral descriptors,…

• ZEHRA ÜSTÜN

Objective: The reasons and characteristics of drug recalls by TITCK between 2018-2024 were analysed. Materials and Methods: A retrospective analysis of drug recalls between 2018-2024 was conducted on the TITCK website. Data on drug recalls were investigated and systematically listed. Data were analysed by year for the…

• TOLGAY ERCAN

Abstract An HPLC–UV method was developed for the simultaneous determination of six phosphodiesterase-5 enzyme inhibitors, namely sildenafil, tadalafil, avanafil, vardenafil, udenafil and mirodenafil, in traditional herbal products and an energy drink. Chromatographic separation was achieved on an ODS3 column with grad…

• KENAN DOST