Article detail · 2026
Isolation and Characterization of New Tadalafil Analogues in Male Sexual Herbal Supplements
- Year
- 2026
- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- YÖKSİS venue Drug Testing and Analysis
- Catalog match (ISSN) Drug Testing and Analysis
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
OpenAlex · English
ABSTRACT New tadalafil analogues were found to be added illegally to an herbal supplement marketed for the enhancement of sexual function. The compounds were separated using flash column chromatography. The structures of the detected tadalafil analogues were elucidated by HPLC‐DAD/MS and nuclear magnetic resonance (NMR) spectroscopy. A protonated molecule at m/z 450.16 was detected by LC–MS, corresponding to a molecular formula of C 24 H 23 N 3 O 6 for both of the diastereomeric compounds. These unknown compounds ( 1 and 2 ) were identified as tadalafil analogues containing an additional dihydroxyethyl group and were named N ‐(2,3‐dihydroxypropyl)nortadalafil.
Topics
Citations
OpenAlex cited_by_count. Not a WoS or Scopus citation count; those sources have no separate column here.
0 citations
OpenAlex cited_by_count (cache / database)