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OpenAlex topic

interferon and immune responses

This page lists works and academicians tagged with an OpenAlex topic. It is not a YÖKSİS primary or secondary field.

OpenAlex 988 works 14 author topics

Works

988 works

  1. Loss of function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early onset autoinflammatory disease 2016
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 1% OpenAlex 99.5%

    No abstract yet.

  2. Characterization of human disease phenotypes associated with mutations in TREX1 RNASEH2A RNASEH2B RNASEH2C SAMHD1 ADAR and IFIH1 2015
    YÖKSİS SJR Q2 JCR Q3 OpenAlex top 1% OpenAlex 99.7%

    Aicardi-Goutières syndrome is an inflammatory disease occurring due to mutations in any of TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR or IFIH1. We report on 374 patients from 299 families with mutations in these seven genes. Most patients conformed to one of two fairly stereotyped clinical profiles; either exhi…

  3. Major Apoptotic Mechanisms and Genes Involved in Apoptosis 2016
    YÖKSİS SJR Q1 JCR Q2 OpenAlex top 1% OpenAlex 99.8%

    No abstract yet.

  4. Human intracellular ISG15 prevents interferon over amplification and auto inflammation 2014
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 1% OpenAlex 99.9%

    No abstract yet.

  5. Familial Mediterranean fever 2005
    OpenAlex top 10% OpenAlex 91.4%

    No abstract yet.

  6. Mutation frequency of Familial Mediterranean Fever and evidence for a high carrier rate in the Turkish population 2001
    YÖKSİS SJR Q1 JCR Q2 OpenAlex 82.5%

    No abstract yet.

  7. The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage 2005
    OpenAlex top 10% OpenAlex 95.0%

    BACKGROUND: Members of the p47 (immunity-related GTPases (IRG) family) GTPases are essential, interferon-inducible resistance factors in mice that are active against a broad spectrum of important intracellular pathogens. Surprisingly, there are no reports of p47 function in humans. RESULTS: Here we show that the p47 G…

  8. Cell surface Death Receptor signaling in normal and cancer cells 2003
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 10% OpenAlex 98.6%

    No abstract yet.

  9. STING-dependent sensing of self-DNA drives silica-induced lung inflammation 2018
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 10% OpenAlex 98.0%

    Silica particles induce lung inflammation and fibrosis. Here we show that stimulator of interferon genes (STING) is essential for silica-induced lung inflammation. In mice, silica induces lung cell death and self-dsDNA release in the bronchoalveolar space that activates STING pathway. Degradation of extracellular self…

  10. STING-dependent sensing of self-DNA drives silica-induced lung inflammation 2018
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 10% OpenAlex 98.0%

    Silica particles induce lung inflammation and fibrosis. Here we show that stimulator of interferon genes (STING) is essential for silica-induced lung inflammation. In mice, silica induces lung cell death and self-dsDNA release in the bronchoalveolar space that activates STING pathway. Degradation of extracellular self…

  11. Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors 2016
    OpenAlex top 10% OpenAlex 98.9%

    No abstract yet.

  12. Familial Mediterranean fever, from pathogenesis to treatment: a contemporary review 2020
    OpenAlex top 10% OpenAlex 97.5%

    Familial Mediterranean fever (FMF) (OMIM #249100) is the most common hereditary autoinflammatory disease in the world. FMF is caused by gain of function mutations of MEFV gene which encodes an immune regulatory protein, pyrin. Over the last few years, we have witnessed several new developments in the pathogenesis, gen…

Academicians

14 academicians