Article detail · 2024
1,2,4-Triazole-conjugated Fluoroquinolones as Potential Candidates for New Antibacterial Agents
YÖKSİS
OpenAlex
SJR Q4
JCR Q4
Citations 0
Percentile 0.6%
FWCI 0.0
- Year
- 2024
- ISSN
1570-1786- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
English (OpenAlex)
Abstract: In this study, synthesis of 1,2,4 triazole-fluoroquinolone hybrid compounds was realized. 7a-d hybrid compound was obtained as a result of mannich reaction with 6a-b triazole compounds norfloxacin and ciprofloxacin. 1H-NMR, 13C-NMR, Mass Spectrometry and Elemental Analysis confirmed the structures of all synthesized compounds. The antimicrobial activities of all compounds were investigated, and it was observed that 7a-d compounds, which are mannich bases, showed excellent activity.
Topics
- Cancer therapeutics and mechanisms
- Synthesis of β-Lactam Compounds
- Tuberculosis Research and Epidemiology
Primary topic Cancer therapeutics and mechanisms