Article detail · 2024
Toward a common interpretation of the 3Rs principles in animal research
- Year
- 2024
- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- YÖKSİS venue Lab Animal
- Catalog match (ISSN) Lab Animal
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
OpenAlex · English
Many scientific breakthroughs have depended on animal research, yet the ethical concerns surrounding the use of animals in experimentation have long prompted discussions about humane treatment and responsible scientific practice. First articulated by Russell and Burch, the 3Rs Principles of Replacement, Reduction, and Refinement have gained widespread recognition as basic guidelines for animal research. Over time, the 3Rs have transcended the research community, influencing policy decisions, animal welfare advocacy and public perception of animal experimentation. Despite their broad acceptance, interpretations of the 3Rs vary substantially, shaping statutory frameworks at various levels, with both technical and practical impacts.
Topics
Citations
OpenAlex cited_by_count. Not a WoS or Scopus citation count; those sources have no separate column here.
65 citations
OpenAlex cited_by_count (cache / database)
4 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).
- Embolization-on-a-chip: novel vascularized liver tumor model for evaluation of cellular and cytokine response to embolic agents 2025
- The Istanbul Workshop organised by the ‘IMPROVE’ COST Action Ethics Crossover Group 2025
- Emerging bioethical conflicts: One Health and animal experimentation 2026
- Veterinary students' ethical judgments on laboratory animal research: A vignette-based study of the 3Rs, ethical review, and animal welfare 2026