Evaluation of Systemic Inflammatory Marker in Patients with Laryngopharyngeal Reflux

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Abstract Aim: It was aimed to investigate whether systemic inflammation markers have diagnostic value in laryngopharyngeal reflux disease. Materials and Methods: This retrospective study was conducted including 32 patients with laryngopharyngeal reflux and 27 subjects with vocal cord nodul. Patients with laryngopharyngeal reflux were evaluated as Group 1, and subjects with vocal cord nodul as Group 2. Patient files were scanned. Neutrophil/lymphocyte ratio, platelet/lymphocyte ratio and systemic inflammation index values were calculated. In addition, the previously filled Reflux symptom index and the Reflux sign scores performed by videoendoscopic examination were noted. Results: While the mean age was 43.21±13.26 years in Group 1, it was 38.04±10.39 years in Group 2. While there were 12 male and 20 female patients in Group 1, there were 12 male and 15 female patients in Group 2. When Neutrophil/lymphocyte ratio, platelet/lymphocyte ratio and systemic inflammation index values were examined, no statistically significant difference was found between Group 1 and Group 2 (p>0.05). Reflux symptom index and Reflux sign scores were significantly higher in Group-1 (p<0.05). There was a significant positive correlation between Reflux symptom index and Reflux sign scores. Conclusion: In our study, no significant difference was found in the Neutrophil/lymphocyte ratio, platelet/lymphocyte ratio and systemic inflammation index values used in the follow-up of many diseases compared to the control group in laryngopharyngeal reflux patients and and had no diagnostic value. While Reflux symptom index and Reflux sign scores were found to be significantly higher in laryngopharyngeal reflux patients compared to the control group, they were significantly positively correlated with each other. KeyWords: Laryngopharyngeal Reflux; Lymphocyte ; Neutrophil; Reflux Symptom Index; Reflux Finding Score