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Article detail · 2000

Critical advances in septicemia and septic shock.

Journal

Critical Care
OpenAlex Open access · gold SJR Q1 JCR Q1 Citations 84 Percentile 80.9% FWCI 1.5
Year
2000
DOI
10.1186/cc711
Type
article

Data source split

  • YÖKSİS venue Critical Care
  • OpenAlex OpenAlex enrichment (abstract, citations, topics)

OpenAlex record

Abstract

OpenAlex · English

Recent advances suggest that toll-like receptors, various cytokines, cicosanoids, free radicals and macrophage migration inhibitory factor (MIF) play an important role in the pathobiology of septicemia and septic shock. Anti-MIF antibodies can decrease the plasma concentrations of tumor necrosis factor (TNF), lower bacterial circulating counts and enhance survival of animals with septicemia and septic shock. Monocyte expression of MHC-class II antigens, neutrophil expression of the integrin CD11b/CD18 and neutrophil activation can be related to the development of, and/or recovery from, post-operative sepsis. Thus, biological variations in the response of an individual to a given stimulus, appears to determine his/her ability or inability to develop and also recover from sepsis and septic shock. This suggests that it may be possible to predict the development of septicemia and septic shock in a given individual and take appropriate action both to prevent and treat them adequately.

Topics

Citations

OpenAlex cited_by_count. Not a WoS or Scopus citation count; those sources have no separate column here.

84 citations

OpenAlex cited_by_count (cache / database)

10 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).

  1. Is insulin an antiinflammatory molecule? 2001 Citations 140 · OpenAlex
  2. State of the art papers HLA-DR expression, cytokines and bioactive lipids in sepsis 2014 Citations 43 · OpenAlex
  3. Insulin in sepsis and septic shock. 2003 Citations 32 · OpenAlex
  4. Insulin and the critically ill. 2002 Citations 29 · OpenAlex
  5. Is sepsis a pro-resolution deficiency disorder? 2012 Citations 20 · OpenAlex
  6. Insulin in the critically ill with focus on cytokines, reactive oxygen species, HLA-DR expression. 2007 Citations 11 · OpenAlex
  7. Albumin Infusion Therapy in Stroke, Sepsis and the Critically Ill 2008 Citations 7 · OpenAlex
  8. Adenosine in Sepsis and Septic Shock 2003 Citations 3 · OpenAlex
  9. Lysophosphatidylcholine and v-3 Fatty Acids in Sepsis 2004 Citations 1 · OpenAlex
  10. Activation of phospholipase A 2 , excess formation of proinflammatory eicosanoids, decreased generation of lysophosphatidylcholine (LPC) and enhanced lev- 2004 Citations 0 · OpenAlex

Authors

No author information.