Article detail · 2017 · article
Role of vitamin D Binding Protein (VDBP) Gene Polymorphism in Lung Cancer
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- YÖKSİSYÖKSİS article record
- YÖKSİS venueTürk Göğüs Kalp Damar Cerrahisi Dergisi
- Catalog match (ISSN)Turkish Journal of Thoracic and Cardiovascular Surgery
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Abstract
Background: This study aims to investigate the role of different alleles of GC gene in the etiology of lung cancer. Methods: The study included 77 patients with lung cancer (73 males, 4 females; mean age 59.6±9.2 years; range 21 to 72 years) and 25 healthy individuals (21 males, 4 females; mean age 47.3±5.4 years; range 23 to 61 years). Polymorphisms in vitamin D binding protein gene of all participants were examined by polymerase chain reaction-restriction fragment length polymorphism method. Results: Of the patients, the genotype 1S-2 was found in 32.4%, 1F-1S in 28.6%, 1S-1S in 28.6%, 1F-2 in 7.8% and 1F-1F in 2.6%, while the genotype frequencies in control group were 28%, 24%, 36%, 4% and 8%, respectively (p=0.35). Conclusion: We did not detect any relationship between vitamin D binding protein gene polymorphisms and lung cancer.
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2 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).
- 2020 Investigation of Critical Genetic Variations of Vitamin D Metabolism and Vitamin D Serum Levels in Brain Cancer-D Vitamini Serum Düzeyleri ile D Vitamini Metabolizmasındaki Kritik Genlere Ait Varyasyonların Beyin Kanserinde İncelenmesiCitations 0 · OpenAlex
- 2020 Investigation of Critical Genetic Variations of Vitamin D Metabolism and Vitamin D Serum Levels in Brain CancerCitations 0 · OpenAlex