Article detail · 2012
Synthesis and application of L-proline andR-phenylglycine derived organocatalysts for directasymmetric Michael addition of cyclohexanone tonitroalkenes
YÖKSİS
OpenAlex
Open access · bronze
SJR Q3
JCR Q3
TR Index
Citations 4
Percentile 0.5%
FWCI 0.0
- Year
- 2012
- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- YÖKSİS venue TURKISH JOURNAL OF CHEMISTRY
- Catalog match (ISSN) Turkish Journal of Chemistry
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
English (OpenAlex)
Novel R-phenylglycine derived organocatalysts were prepared from the reaction of Cbz-R-phenylglycine with indoline, pyrrolidine, or (S)-(-)-2-(diphenylmethyl)pyrrolidine in 3 steps. The asymmetric Michael addition of cyclohexanone to nitroolefins was investigated using R-phenylglycine derivatives along with L-prolinamides as chiral catalysts. The desired products were obtained in excellent yields with enantioselectivities up to 90% ee and diastereomeric ratio up to 98:2 of the syn }addition product.
Topics
- Asymmetric Synthesis and Catalysis
- Analytical Chemistry and Chromatography
- Asymmetric Hydrogenation and Catalysis
Primary topic Asymmetric Synthesis and Catalysis