Makale detayı · 2012
Synthesis and application of L-proline andR-phenylglycine derived organocatalysts for directasymmetric Michael addition of cyclohexanone tonitroalkenes
YÖKSİS
OpenAlex
Açık erişim · bronze
SJR Q3
JCR Q3
TR Index
Atıf 4
Yüzdelik 0.5%
FWCI 0.0
- Yıl
- 2012
- ISSN
1300-0527- Tür
- article
Veri kaynağı ayrımı
- YÖKSİS YÖKSİS makale kaydı
- OpenAlex OpenAlex zenginleştirmesi (özet, atıf, konular)
Özet
İngilizce (OpenAlex)
Novel R-phenylglycine derived organocatalysts were prepared from the reaction of Cbz-R-phenylglycine with indoline, pyrrolidine, or (S)-(-)-2-(diphenylmethyl)pyrrolidine in 3 steps. The asymmetric Michael addition of cyclohexanone to nitroolefins was investigated using R-phenylglycine derivatives along with L-prolinamides as chiral catalysts. The desired products were obtained in excellent yields with enantioselectivities up to 90% ee and diastereomeric ratio up to 98:2 of the syn }addition product.
Konular
- Asymmetric Synthesis and Catalysis
- Analytical Chemistry and Chromatography
- Asymmetric Hydrogenation and Catalysis
Birincil konu Asymmetric Synthesis and Catalysis