Article detail · 2024
All-in-One Nanohybrids Combining Sonodynamic Photodynamic and Photothermal Therapies
- Year
- 2024
- ISSN
2576-6422- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
English (OpenAlex)
High Resolution Image Download MS PowerPoint Slide A wide variety of methods are being developed to ultimately defeat cancer; while some of these strategies have shown highly positive results, there are serious obstacles to overcome to completely eradicate this disease. So, it is crucial to construct multifunctional nanostructures possessing intelligent capabilities that can be utilized to treat cancer. A possible strategy for producing these multifunctional nanostructures is to combine various cancer treatment techniques. Based on this point of view, we successfully synthesized multifunctional HCuS@Cu 2 S@Au–P(NIPAM- co -AAm)-PpIX nanohybrids. The peculiarities of these thermosensitive polymer-modified and protoporphyrin IX (PpIX)-loaded hollow nanohybrids are that they combine photodynamic therapy (PDT), sonodynamic therapy (SDT), and photothermal therapy (PTT) with an intelligent design. As an all-in-one nanohybrids, HCuS@Cu 2 S@Au–P(NIPAM- co -AAm)-PpIX nanohybrids were employed in the SDT–PDT–PTT combination therapy, which proved to have a synergistic therapeutic effect for in vitro tumor treatments against breast tumors.
Topics
- Nanoplatforms for cancer theranostics
- Photoacoustic and Ultrasonic Imaging
- Photodynamic Therapy Research Studies
Primary topic Nanoplatforms for cancer theranostics