Article detail · 2011
Interleukin 17 and interleukin 18 levels in saliva and plasma of patients with chronic periodontitis
- Year
- 2011
- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- YÖKSİS venue Journal of Periodontal Research
- Catalog match (ISSN) Journal of Periodontal Research
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
OpenAlex · English
BACKGROUND AND OBJECTIVE: This study was planned to investigate whether patients with chronic periodontitis exhibit different salivary and/or plasma concentrations of interleukin (IL)-17 and IL-18 compared with clinically healthy subjects. MATERIAL AND METHODS: Whole saliva and blood samples, together with full-mouth clinical periodontal recordings, were obtained from 22 otherwise healthy untreated nonsmokers with chronic periodontitis and from 21 systemically and periodontally healthy control subjects. The concentrations of IL-17 and IL-18 in saliva and plasma were determined using ELISAs. RESULTS: The healthy control group exhibited significantly lower values in all clinical periodontal measurements (p < 0.001). The salivary concentration of IL-17 was significantly lower, and that of IL-18 significantly higher, in patients from the chronic periodontitis group compared with healthy control subjects (p = 0.025 and p = 0.009, respectively). Plasma IL-17 and IL-18 concentrations were similar in the two study groups (p > 0.05). CONCLUSION: Within the limits of the present study, it may be suggested that an elevated salivary IL-18 level in untreated nonsmoker chronic periodontitis patients has the potential to be a biomarker for periodontal tissue destruction.
Topics
Citations
OpenAlex cited_by_count. Not a WoS or Scopus citation count; those sources have no separate column here.
97 citations
OpenAlex cited_by_count (cache / database)
34 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).
- Is Interleukin-17 Involved in the Interaction Between Polycystic Ovary Syndrome and Gingival Inflammation? 2013
- Is Interleukin 17 Involved in the Interaction Between Polycystic Ovary Syndrome and Gingival Inflammation 2013
- Is interleukin 17 involved in the interaction between polycystic ovary syndrome and gingival inflammation 2013
- Evaluation of Local and Systemic Levels of Interleukin 17 Interleukin 23 and Myeloperoxidase in Response to Periodontal Therapy in Patients with Generalized Aggressive Periodontitis 2015
- Evaluation of Local and Systemic Levels of Interleukin 17 Interleukin 23 and Myeloperoxidase in Response to Periodontal Therapy in Patients with Generalized Aggressive Periodontitis 2015
- Evaluation of Local and Systemic Levels of Interleukin 17 Interleukin 23 and Myeloperoxidase in Response to Periodontal Therapy in Patients with Generalized Aggressive Periodontitis 2015
- Evaluation of Local and Systemic Levels of Interleukin 17 Interleukin 23 and Myeloperoxidase in Response to Periodontal Therapy in Patients with Generalized Aggressive Periodontitis 2015
- Altered Antigenic Profiling and Infectivity of Porphyromonas gingivalis in Smokers and Non Smokers With Periodontitis 2014
- The Gingival Crevicular Fluid Levels of Interleukin 11 and Interleukin 17 in Patients With Aggressive Periodontitis 2012
- The Gingival Crevicular Fluid Levels of Interleukin 11 and Interleukin 17 in Patients With Aggressive Periodontitis 2012