Makale detayı · 2011
Interleukin 17 and interleukin 18 levels in saliva and plasma of patients with chronic periodontitis
- Yıl
- 2011
- Tür
- article
Veri kaynağı ayrımı
- YÖKSİS YÖKSİS makale kaydı
- YÖKSİS dergi adı Journal of Periodontal Research
- Katalog eşleşmesi (ISSN) Journal of Periodontal Research
- OpenAlex OpenAlex zenginleştirmesi (özet, atıf, konular)
Özet
OpenAlex · İngilizce
BACKGROUND AND OBJECTIVE: This study was planned to investigate whether patients with chronic periodontitis exhibit different salivary and/or plasma concentrations of interleukin (IL)-17 and IL-18 compared with clinically healthy subjects. MATERIAL AND METHODS: Whole saliva and blood samples, together with full-mouth clinical periodontal recordings, were obtained from 22 otherwise healthy untreated nonsmokers with chronic periodontitis and from 21 systemically and periodontally healthy control subjects. The concentrations of IL-17 and IL-18 in saliva and plasma were determined using ELISAs. RESULTS: The healthy control group exhibited significantly lower values in all clinical periodontal measurements (p < 0.001). The salivary concentration of IL-17 was significantly lower, and that of IL-18 significantly higher, in patients from the chronic periodontitis group compared with healthy control subjects (p = 0.025 and p = 0.009, respectively). Plasma IL-17 and IL-18 concentrations were similar in the two study groups (p > 0.05). CONCLUSION: Within the limits of the present study, it may be suggested that an elevated salivary IL-18 level in untreated nonsmoker chronic periodontitis patients has the potential to be a biomarker for periodontal tissue destruction.
Konular
Atıflar
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97 atıf
OpenAlex cited_by_count (önbellek / veritabanı)
Yerel katalogda bu makaleye atıf yapan 28 yayın (OpenAlex referans eşleşmesi; tam dünya listesi değildir).
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- Evaluation of Local and Systemic Levels of Interleukin 17 Interleukin 23 and Myeloperoxidase in Response to Periodontal Therapy in Patients with Generalized Aggressive Periodontitis 2015
- Evaluation of Local and Systemic Levels of Interleukin 17 Interleukin 23 and Myeloperoxidase in Response to Periodontal Therapy in Patients with Generalized Aggressive Periodontitis 2015
- Evaluation of Local and Systemic Levels of Interleukin 17 Interleukin 23 and Myeloperoxidase in Response to Periodontal Therapy in Patients with Generalized Aggressive Periodontitis 2015
- Altered Antigenic Profiling and Infectivity of Porphyromonas gingivalis in Smokers and Non Smokers With Periodontitis 2014
- Association between Polycystic Ovary Syndrome Oral Microbiota and Systemic Antibody Responses 2014
- Is obesity a possible modifier of periodontal disease as a chronic inflammatory process A case control study 2014
- The Gingival Crevicular Fluid Levels of Interleukin 11 and Interleukin 17 in Patients With Aggressive Periodontitis 2012