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OpenAlex topic

PARP inhibition in cancer therapy

This page lists works and academicians tagged with an OpenAlex topic. It is not a YÖKSİS primary or secondary field.

OpenAlex 810 works 14 author topics

Works

596 works

  1. Chemotherapy with or without pembrolizumab followed by maintenance pembrolizumab with or without olaparib as first-line treatment of patients with advanced BRCA non-mutated epithelial ovarian cancer (ENGOT-OV43/GOG-3036/KEYLYNK-001): a randomised, double-blind, placebo-controlled, phase 3 trial 2026

    No abstract yet.

  2. Hepatitis B Reactivation During Ribociclib Therapy in a Patient with Metastatic Breast Cancer 2026

    Cite this article as: Demiral YE, Günegül Y, Eminler AT, Tozlu M, Uslan Mİ. Hepatitis B reactivation during ribociclib therapy in a patient with metastatic breast cancer. Turk J Gastroenterol. Published online June 3, 2026. doi: 10.5152/tjg.2026.26186.

  3. CSB-independent, XPC-dependent transcription-coupled repair in Drosophila 2026

    Drosophila melanogaster has been extensively used as a model system to study ionizing radiation and chemical-induced mutagenesis, double-strand break repair, and recombination. However, there are only limited studies on nucleotide excision repair in this important model organism. An early study reported that Drosophil…

  4. Abstract 5214: The mutational landscape underlying the late effects of anthracyclines on tumor, blood, and heart genomes 2026

    Abstract Motivation: Anthracyclines, an essential chemotherapy, disproportionately contributes to several late effects burdening survivors of cancer, including cancer relapse, therapy-related blood cancers, and fatal cardiotoxicity. Despite decades of clinical use, the mechanisms underlying these late effects - partic…

  5. Nicotinamide Adenine Dinucleotide and Its Anti-aging Effects in the Context of Longevity and Menopause 2026

    Menopause is a complex biological condition associated with progressive estrogen depletion and increased susceptibility to several age-associated disorders. During this process, several biological mechanisms, such as mitochondrial dysfunction, oxidative stress, chronic inflammation, genomic instability, and immunosene…

  6. Nicotinamide Adenine Dinucleotide (NAD⁺) and the Biology of Aging Mechanisms of Decline and Therapeutic Restoration 2026

    The inexorable process of aging is underpinned by a cascade of molecular deficits that erode cellular homeostasis and organismal function. A pivotal molecule within this cascade is nicotinamide adenine dinucleotide (NAD⁺), a fundamental redox cofactor in energy metabolism and an essential substrate for signaling enzym…

  7. Abstract PS1-11-04: Her2-low expression is associated with inferior progression-free survival in hr-positive metastatic breast cancer treated with CDK4/6 inhibitors 2026

    Abstract Background: CDK4/6 inhibitors have become a standard treatment option for patients with hormone receptor-positive (HR+), HER2-negative metastatic breast cancer. However, there remains a need for reliable biomarkers to predict treatment response. Recently, tumors classified as HER2-low have emerged as a distin…

  8. Restoration of miR-188-5p Reverses PARP Inhibitor Resistance in High-Grade Serous Ovarian Cancer via Apoptosis Induction and DNA Repair Suppression 2026

    No abstract yet.

  9. Real-World Outcomes of CDK4/6 Inhibitors in Germline BRCA-Mutated Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer: Turkish Oncology Group (TOG) Study 2026

    No abstract yet.

  10. Exploring the therapeutic potential of NCX1 in hematological cancers; integration of molecular docking, bioinformatics approaches, and experimental validation 2026

    No abstract yet.

  11. Targeting the NAD+ salvage pathway: Identification of bifunctional NAMPT inhibitors and SIRT1 activators through pharmacophore-based virtual screening 2026

    No abstract yet.

  12. A Functional Evaluation of Resveratrol–Paclitaxel Combination Reveals Enhanced Apoptotic Responses in HeLa Cells 2026

    This study evaluated the combined effects of resveratrol (RES) and paclitaxel (PAC) on cell viability, apoptotic responses, and associated cellular processes in HeLa cervical cancer cells. Antiproliferative activity was assessed using XTT assay and combination index (CI) analysis, while apoptosis, cell cycle distribut…

Academicians

14 academicians