HIV-related health complications and treatments

In recent years, the global increase in drug resistance rates against antiretroviral therapy (ART) regimens has underscored the importance of incorporating HIV drug resistance testing into routine clinical practice and its critical role in treatment success. The aim of this study was to determine HIV drug resistance a…

BACKGROUND: Tenofovir alafenamide (TAF) is widely used in antiretroviral therapy due to its improved renal and bone safety compared to tenofovir disoproxil fumarate (TDF). However, concerns remain regarding its potential metabolic effects and cardiovascular risk. We aimed to compare lipid parameters and surrogate mark…

BACKGROUND: Nutritional disorders are common in patients with Alcohol Use Disorder (AUD) or Substance Use Disorder (SUD) and can lead to vitamin deficiencies such as Folate Deficiency (FD). The aim of this study was to investigate folate levels and the presence of FD in AUD or SUD patients by comparing them according…

The journal retracts the article titled "Assessing the In Vitro and In Vivo Performance of L-Carnitine-Loaded Nanoparticles in Combating Obesity [...].

Introduction: Cytomegalovirus (CMV) remains latent in about half of adults and may reactivate in immunocompromised individuals.In advanced HIV infection, CMV can cause systemic disease with end-organ involvement.Case Presentation: A 34-year-old woman with newly diagnosed HIV who had recently started antiretroviral the…

Human immunodeficiency virus (HIV) infection causes gut epithelial barrier dysfunction and dyslipidemia. Intestinal fatty acid-binding protein (I-FABP) and regenerating islet-derived protein 3 alpha (REG3α) are markers of gut barrier integrity. We investigated the association between these biomarkers and LDL-cholester…

The purpose of this study is to investigate the relationship between hand grip strength (HGS) and erectile dysfunction (ED) in men over 40 years old. The study aims to determine if HGS can serve as an indicator of ED severity and associated health conditions. In this study, 301 male participants were assessed for ED a…

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Human immunodeficiency virus (HIV) is increasingly managed as a chronic condition, making health-related quality of life (HRQoL) an important long-term care outcome. The proposed “fourth 90” emphasises good quality of life among virally suppressed people. This study assessed HRQoL and examined associations with sociod…

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Yirminci ve yirmi birinci yüzyılda biyoloji ve tıp alanlarında yaşanan ilerlemeler, dünya genelinde sağlık yükünün yapısını önemli ölçüde değiştirmiştir. Enfeksiyon hastalıkları önemini korumakla birlikte, günümüzde yaşam biçimiyle ilişkili kronik hastalıklar halk sağlığı açısından giderek daha büyük bir tehdit oluştu…

Yirminci ve yirmi birinci yüzyılda biyoloji ve tıp alanlarında yaşanan ilerlemeler, dünya genelinde sağlık yükünün yapısını önemli ölçüde değiştirmiştir. Enfeksiyon hastalıkları önemini korumakla birlikte, günümüzde yaşam biçimiyle ilişkili kronik hastalıklar halk sağlığı açısından giderek daha büyük bir tehdit oluştu…