Inhalation and Respiratory Drug Delivery

The GOLD 2025 guideline was developed as an essential reference for managing Chronic Obstructive Pulmonary Disease (COPD) based on current scientific evidence. It comprehensively addressed COPD pathogenesis, diagnosis, personalized treatment strategies, novel bronchodilator therapies, vaccination programs, and pulmona…

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Aims: To determine whether active smokers with preserved post-bronchodilator spirometry (FEV₁/FVC ≥ lower limit of normal [LLN]) and normal thoracic computed tomography (CT) show lower FEF₂₅₋₇₅ values and a higher prevalence of isolated small airway dysfunction than never-smokers, and to assess PEF-FEV₁ agreement for…

Aims: To determine whether active smokers with preserved post-bronchodilator spirometry (FEV₁/FVC ≥ lower limit of normal [LLN]) and normal thoracic computed tomography (CT) show lower FEF₂₅₋₇₅ values and a higher prevalence of isolated small airway dysfunction than never-smokers, and to assess PEF-FEV₁ agreement for…

Objective: The use of medium and low-dose inhaled corticosteroids (ICS) did not increase the risk of osteoporosis in individuals with chronic obstructive pulmonary disease (COPD). The goal is to look at the risk of osteoporosis that comes with Budesonide and Fluticasone when choosing ICS for people with COPD, since th…

We, the authors, are delighted that Mehta and Sah reviewed our article examining the interaction between learning needs and care dependency in individuals with chronic obstructive pulmonary disease (COPD) with great interest and considered it evidence contributing to future research. We also consider the suggestions f…

Background & Objective: Asthma control depends largely on adherence to inhaled controller therapy and correct inhaler technique, yet both remain suboptimal in routine practice. Telemedicine-based monitoring has emerged as a feasible strategy to support patient education and adherence. This pilot study aimed to evaluat…

Objective The presence of fine dusts in the industrial working environment has significant implications for occupational safety. As a result, legislators have implemented regulations to protect employees from adverse lung effects. The establishment of limits aims to prevent health hazards, particularly lung diseases,…

Background: Childhood obesity can cause changes in respiratory mechanics, particularly in the peripheral airways. This study aimed to evaluate impulse oscillometry (IOS) parameters in obese children and to investigate the relationship between small airway function and metabolic indicators. Methods: A total of 135 chil…

Background/Objectives: Non-Hodgkin Lymphoma (NHL) remains a challenging malignancy where treatment success is often limited by drug resistance and severe side effects, even with the standard R-CHOP regimen. In this study, rituximab (RTX)-conjugated nanoparticles (NPs) enhance mitochondrial accumulation of their cargo,…

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