Venomous Animal Envenomation and Studies

Snakebite envenomation remains a significant cause of morbidity worldwide, with local tissue complications representing a major determinant of long-term functional outcome. Severe manifestations such as progressive necrosis, compartment syndrome, and chronic non-healing wounds frequently require surgical and reconstru…

Excessive generations of apoptosis and oxygen free radicals (OFRs) are two main common reasons of age-related macular degeneration (AMD). A homeopathic preparation of the Tarantula Cubensis spider venom is Theranekron (TNE). The antiapoptotic and antioxidant actions of TNE were indicated in different disease models ex…

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The causative agent of American foulbrood, Paenibacillus larvae, is a leading cause of significant losses in beekeeping. In this study, the agent was isolated, its bacteriological characteristics were identified, and the expression levels of antibiotic resistance genes were determined. The study also assessed the anti…

Hirudoterapi, tıbbi sülüklerin biyolojik aktif bileşenleri aracılığıyla sağlığa olumlu etkiler sunduğu bir geleneksel ve tamamlayıcı tıp uygulamasıdır. Tarihsel olarak antik çağlardan itibaren çeşitli hastalıkların düzeltilmesinde kullanılan bu yöntem, günümüzde cerrahi sonrası dolaşım bozuklukları, venöz konjesyon ve…

Bee venom (BV) is valued therapeutically mainly for its peptides, melittin and apamin. This study determined the dose-dependent biological activity of bee venom standardized to its melittin and apamin content by UHPLC-ESI-MS, as well as that of its principal peptides, melittin and apamin, tested at matched concentrati…

Thymotrinan is an immunomodulating tripeptide containing the Arg-Lys-Asp sequence.In this study, the structural, vibrational, and electronic properties, as well as the bioactivity of thymotrinan, have been thoroughly examined.The conformational preferences of thymotrinan were evaluated through conformational analysis,…

Objective: The impact of anatomical bite location on snakebite envenomation severity and clinical outcomes remains unclear. This study aimed to compare the clinical characteristics, treatment requirements, and outcomes of upper and lower extremity snakebites. Methods: This retrospective study included adult patients p…

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Introduction: Colorectal cancer (CRC) is one of the most common malignancies worldwide and remains a leading cause of cancer-related mortality, particularly when diagnosed at advanced stages. The search for novel anticancer agents derived from natural products has attracted increasing attention, with scorpion venoms r…

Scorpion stings are generally associated with local symptoms, but they may also cause systemic toxicity, including clinically significant cardiac involvement. We report an 84-year-old woman with a history of hypertension who presented to the emergency department (ED) after a scorpion sting to the left great toe. Her i…

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