Allergic Rhinitis and Sensitization

This narrative review examines the clinical and immunological relationship between asthma and chronic rhinosinusitis (CRS), with particular emphasis on shared type 2 inflammatory pathways, biomarkers, genetic associations, and the “united airway” concept. It also evaluates medical, surgical, and biologic treatment app…

This narrative review examines the clinical and immunological relationship between asthma and chronic rhinosinusitis (CRS), with particular emphasis on shared type 2 inflammatory pathways, biomarkers, genetic associations, and the “united airway” concept. It also evaluates medical, surgical, and biologic treatment app…

For transparency, the peer review documents associated with this article are available at https://doi.org/10.1111/pai.70330. The data that support the findings of this study are available from the corresponding author upon reasonable request. Appendix S1. Table S1. Table S2. Table S3. Please note: The publisher is not…

Curcumin, a flavonoid derived from turmeric, has demonstrated antioxidant, anti-inflammatory, and antiallergic effects. This study evaluated the therapeutic efficacy of intranasal curcumin in an allergic rhinitis (AR) rat model. Forty rats were randomized into four groups: a sham control, an AR model with no treatment…

Amaç: Çocukluk çağı hastalıklarının önemli bir bölümünü oluşturan besin alerjileri bağışıklık sisteminin besinlere karşı anormal yanıt vermesi sonucunda oluşan hastalıklar grubudur. Bu çalışma, Çocuk Alerji Polikliniği’nde Besin proteini ilişkili alerjik proktokolit tanısı ile izlenen olguların klinik ve demografik öz…

SCOPE: Antibiotic allergies remain one of the most frequently documented drug allergies in clinical records. It is well established that only a small proportion-estimated at 5% to 10%-represents true immune-mediated hypersensitivity. Mislabelling can contribute to the development of antimicrobial resistance via prescr…

Aim: This study aimed to assess the effectiveness of mepolizumab in enhancing asthma control, achieving clinical remission, and alleviating upper airway symptoms in patients with severe eosinophilic asthma (SEA) with comorbid nasal polyps and/or chronic rhinosinusitis (CRS). Additionally, it aimed to identify clinical…

INTRODUCTION: The Chronic Rhinosinusitis Control Test (CRCT) is a patient-reported outcome measure (PROM) written in English that is psychometrically validated to measure chronic rhinosinusitis control. Because the availability of translated PROMs is a driver of data equity-collection of data that is fair and generall…

Background: Cat sensitization is common in patients with allergic diseases and may not always produce clinical symptoms. Objective: This study aimed to assess the correlation between skin prick test (SPT), cat-specific immunoglobulin E (cat sIgE), and symptoms in sensitized children, and to determine optimal threshold…

PURPOSE: This study aimed to analyze ocular sur-face parameters and evaluate meibomian gland dys-function using meibography in newly diagnosed patients with atopic dermatitis compared with healthy controls. METHODS: This cross-sectional clinical study included 51 newly diagnosed patients with atopic dermatitis and 45…

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OBJECTIVE: Rhinitis is a common upper airway disorder, classified as either allergic rhinitis (AR) or non-allergic rhinitis (NAR).While the association between air pollution and AR airway diseases has been well documented, its specific effects on NAR remain poorly understood.This study aimed to evaluate the seasonal i…