Folate and B Vitamins Research

ABSTRACT Growth retardation, defined by impaired anthropometric development relative to age‐based population standards, may be accompanied by metabolic alterations. This study aimed to characterize serum and urine metabolomic profiles in children with growth retardation using exploratory 1 H‐NMR spectroscopy. Thirty c…

• METİN DEMİREL

The enzyme glucose-6-phosphate dehydrogenase (G6PD, EC 1.1.1.49) is the first and rate-limiting enzyme of the pentose phosphate pathway, which is essential for the integrity and function of red blood cells. NADPH, produced in this metabolic pathway, acts as a protector of anabolic pathways in the liver and plays a cru…

The enzyme glucose-6-phosphate dehydrogenase (G6PD, EC 1.1.1.49) is the first and rate-limiting enzyme of the pentose phosphate pathway, which is essential for the integrity and function of red blood cells. NADPH, produced in this metabolic pathway, acts as a protector of anabolic pathways in the liver and plays a cru…

The enzyme glucose-6-phosphate dehydrogenase (G6PD, EC 1.1.1.49) is the first and rate-limiting enzyme of the pentose phosphate pathway, which is essential for the integrity and function of red blood cells. NADPH, produced in this metabolic pathway, acts as a protector of anabolic pathways in the liver and plays a cru…

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OBJECTIVE: This study aimed to evaluate changes in the etiological distribution of pediatric hypertransaminasemia before, during, and after the COVID-19 pandemic and to assess their association with clinical presentation and biochemical severity. METHODS: This retrospective study evaluated temporal changes in the etio…

e15052 Background: Folate and folate receptor alpha (FRα) are critical for cell proliferation and DNA synthesis. FRα is overexpressed in various malignancies, including ovarian and lung cancer. This study aimed to analyze serum folate and FRα levels in colon cancer patients and evaluate their association with diagnosi…

Aim: This study aimed to evaluate the effect of three-month DHA+choline supplementation on infection-related outpatient visits and antibiotic use in children aged 7–15 years.Materials and Methods: This retrospective, observational, two-group cohort study was conducted at 13 independent pediatric centers between Januar…

BACKGROUND: Nutritional disorders are common in patients with Alcohol Use Disorder (AUD) or Substance Use Disorder (SUD) and can lead to vitamin deficiencies such as Folate Deficiency (FD). The aim of this study was to investigate folate levels and the presence of FD in AUD or SUD patients by comparing them according…

OBJECTIVE: Congenital anomalies (CA) are health problems that can significantly affect individuals, families, health systems, and society. Our aim is to present the characteristics of CA observed in babies born at our institution between 2014 and 2023, including the Covid-19 pandemic period. MATERIALS AND METHODS: Ret…

Parabens are used for preservative purposes in various fields, especially in pharmaceutical, cosmetic and food products. Recent studies suggest that parabens may affect oxidative stress mechanisms in biological systems and may cause cellular damage. This experiment was created to better understand the possible biologi…

Abstract Objective To evaluate the clinical significance of folate receptor alpha (FRα) expression in endometrial serous carcinoma. Methods We retrospectively analyzed 47 patients with histopathologically confirmed endometrial serous carcinoma who underwent hysterectomy and received systemic therapy. FRα expression wa…