Renal cell carcinoma treatment

Objective: The clinicopathological characteristics and survival outcomes of rare primary renal tumor cases treated surgically were evaluated and compared with the literature. Material and Methods: A total of 517 patients who underwent partial or radical nephrectomy for renal mass between January 2020-January 2025 were…

Supplementary Material 1.

Supplementary Material 1.

Introduction/Objective: Pazopanib is a key targeted therapy for advanced renal cell carcinoma, yet data on its quantification and degradation behavior in urine are limited. This study aimed to develop and validate a rapid UPLC-DAD method for pazopanib determination in human urine and to investigate its degradation pro…

4526 Background: Despite available tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors (ICIs), reliable biomarkers guiding frontline advanced RCC treatment remain limited. Existing signatures lack generalizability across therapeutic regimens. We developed a data-driven machine learning (ML) framework to…

BACKGROUND: This study aimed to describe the clinicopathological characteristics of renal cell carcinoma (RCC) in young adults (≤ 40 years) and reclassify tumour subtypes in accordance with the 2022 World Health Organization (WHO) classification, with exploratory assessment of outcome-related associations. METHODS: In…

Data sharing is not applicable to this article as no datasets were generated or analyzed during the current study.

To evaluate the clinical outcomes of nephrectomy performed due to renal mass. Cases of nephrectomy performed due to renal mass at the Samsun University Urology Department between 2015 and 2024 were assessed retrospectively through our database. The patients’ sociodemographic characteristics, pre- and postoperative cli…

OBJECTIVE: To assess long-term changes in renal volume and function after laparoscopic partial nephrectomy using 3D modeling and to identify key predictors. PATIENTS AND METHODS: This retrospective study included 187 patients who underwent laparoscopic partial nephrectomy between October 2012 and January 2023. Patient…

Introduction. Wilms tumor is the most common renal malignancy in children. Survival rates now exceed 90% with multimodal therapy. This study aims to retrospectively analyze 104 pediatric Wilms tumor patients diagnosed over a 47-year period at our institution, examining demographic characteristics, tumor staging, treat…

No abstract yet.

Abstract Background Brain metastases (BM) in renal cell carcinoma (RCC) are associated with poor prognosis and limited clinical guidance. We aimed to identify prognostic factors for overall survival (OS) in RCC BM and develop an interpretable machine-learning (ML) model for individualized risk prediction. Methods We r…