Muscle Physiology and Disorders

Platelet-rich plasma (PRP) is commonly used to support skeletal muscle healing, although its efficacy remains variable and concerns persist regarding profibrotic effects. Platelet-derived extracellular vesicles (pEVs) may modulate inflammation, and this study aimed to compare the histological effects of two PRP system…

• BERİL GÜLER VANÇİN

Abstract Titin molecules of skeletal muscle actived muscle gene expression produce active force during passive stiffness indirectly in spring properties. To that the titin activation determines on passive sarcomeres role and active force during molecular lengthening in myofibrils. Titin directly of thick (myosin) and…

Abstract Titin molecules of skeletal muscle actived muscle gene expression produce active force during passive stiffness indirectly in spring properties. To that the titin activation determines on passive sarcomeres role and active force during molecular lengthening in myofibrils. Titin directly of thick (myosin) and…

Objective: This study was conducted to investigate the effects of different severities of wooden breast and white striping myopathies on oxidative stress markers in broiler chickens of Cobb and Ross genotypes.Material and Methods: In the study, a total of 120 pectoralis major muscle samples collected from broiler chic…

Regular exercise is a cornerstone of healthy longevity. Exercise has numerous effects on aging mechanisms, including telomere integrity, mitochondrial function, genomic stability, and inflammatory processes. The literature contains studies investigating the effects of various types of exercise on lifespan and quality…

Objective: Sarcopenia is increasingly recognized as a marker of frailty and a predictor of adverse outcomes in surgical oncology. However, its role in patients undergoing radical prostatectomy (RP) for localized prostate cancer (PCa) remains unclear.Methods: We retrospectively analyzed 165 men who underwent RP between…

Polyphenol-rich tart cherry (TC) supplementation has previously been shown to enhance recovery from exercise-induced muscle damage (EIMD). However, no studies have investigated the effects of different doses of TC supplementation on such recovery. The molecular mechanism(s) of action through which TC elicits these eff…

Diabetes mellitus (DM) is a chronic metabolic disease characterized by hyperglycemia, and the diaphragm—the primary respiratory muscle—is adversely affected by this diabetic process. The aim of this study is to investigate the effects of zinc sulfate (ZnSO4) treatment on diaphragm muscle contractile dynamics, calcium…

PURPOSE. Sarcopenia, the age-related loss of skeletal muscle mass, strength and physical performance, is a leading cause of disability, falls and loss of independence in older adults. Drosophila melanogaster is one of the most widely used invertebrate models of muscle ageing, offering a short lifespan, powerful geneti…

OBJECTIVE: Although free functional muscle transfer (FFMT) has been used in clinical practice for many years, there is no experimental model for FFMT. We aimed to describe a novel experimental muscle flap model and define the triceps brachii free muscle flap as an FFMT model in rats. METHODS: A total of 10 Wistar-Albi…

Skeletal muscle, despite constituting nearly half of human body mass, is rarely affected by metastatic spread. The biological mechanisms underlying this relative resistance remain poorly understood. Dual-specificity phosphatases (DUSPs) have emerged as important regulators in tumor biology; however, the role of DUSP29…

Background Diagnosing facioscapulohumeral muscular dystrophy (FSHD) requires integrated evaluation of D4Z4 repeat size, permissive haplotype status, epigenetic context and alternative molecular aetiologies, particularly in borderline, non-contracted or structurally complex cases. Methods We evaluated 135 unrelated ref…