Carcinogens and Genotoxicity Assessment

Dose-dependent cholinergic, inflammatory, and genotoxic effects of etoxazole in female Wistar rats 2026

Etoxazole is a widely used oxazoline acaricide in agriculture; however, its toxicological profile in mammalian systems remains insufficiently characterized. This study investigated the dose-dependent effects of subchronic etoxazole exposure on serum biochemical, genotoxic, and haematological parameters in female Wista…

Investigation of the Effects of Diplotaenia turcica Root Extract on Sperm Parameters and Antioxidant Markers in Methotrexate-Administered Rats 2026

This experimental study was designed to evaluate the potential toxic effects of Methotrexate (MTX), an antineoplastic agent, on sperm parameters and antioxidant defense mechanisms in rats, as well as to assess the protective potential of Diplotaenia turcica, an endemic plant species from Turkey. A total of 21 male Wis…

The Effect of Diplotaenia turcica Root Extract on Sperm Parameters and Antioxidant Parameters in Doxorubicin-administered Rats 2026

This experimental study was designed to evaluate the potential toxic effects of Doxorubicin (DOX), a commonly used antineoplastic agent, on sperm parameters and antioxidant markers in rats, as well as the potential protective role of the root extract of Diplotaenia turcica, an endemic plant species native to Türkiye.…

Cytogenotoxic and Molecular Assessment of Pyrethrins on Non‐Target Allium cepa Roots 2026

The pyrethrins, which form a part of naturally occurring insecticidal chemicals derived from chrysanthemum flowers, not only provide rapid knockdown of a broad spectrum of insect pests but are also widely used in integrated pest management due to a generally favorable safety profile, largely attributed to low mammalia…

Evaluation of the Anticancer Effects of DODP on Gene Expression and Oxidative Stress in Gastric Cancer: An Integrated Docking, Bioinformatics, and Experimental Approach 2026

(1) Background: Gastric cancer (GC) remains a major global health challenge due to its high heterogeneity and aggressive progression. The discovery of novel bioactive molecules with anticancer properties has, therefore, become a critical research focus. In this study, we synthesized and characterized 4,4′-(5,8-dioxa-2…

Bidirectional regulation of heterocyclic amines by flavonoids: insights from flavonoid amination using dihydromyricetin and baicalein 2026

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Genotoxic potential and health risk assessment of surface and tap waters in the central Black Sea region 2026

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Biogenic amine profiling of fruit wines by high-performance liquid chromatography with fluorescence detection after OPA derivatisation: effect of fruit type 2026

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Biogenic amines as emerging food safety markers: formation pathways, health implications, and mitigation approaches 2026

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Assessment of spermatogenesis following bleomycin treatment in male rat model: The damage and recovery process 2026

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Histopathological Effects of E-Cigarette Aerosols on Seminiferous Tubule Structure, the Blood-Testis Barrier and Steroidogenesis in Testicular Tissue 2026

Objective: To evaluate the histopathological, steroidogenic, redox-related and functional effects of e cigarette aerosol or e-liquid exposure on the testes and male fertility while distinguishing direct e cigarette evidence from comparative mechanistic and clinical-context evidence.Materials and Methods: PubMed and We…

The Protective Effect of Galangin on Histopathological Lesions, Immunohistochemical Findings and Spermatological Parameters in Phthalate‐Induced Testicular Damage in Rats 2026

One of the main causes of the increasing male infertility today is di-(2-ethylhexyl) phthalate (DEHP), which is widely used in plastic production. To investigate testicular damage caused by DEHP and the effect of galangin, used for the first time in this treatment, the protective effect of different doses of galangin…

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