Sarcoma Diagnosis and Treatment

BACKGROUND: While traditional surgical decision-making emphasizes long-term implant survivorship for octogenarians knee reconstruction, this paradigm may be inappropriate when patient mortality risk substantially exceeds revision risk. This study compared mid-term mortality between unicompartmental knee arthroplasty (…

This study aims toevaluate the response ofprimary cells tobuparlisib, aPI3K inhibitor, atvarying concentrations and exposure durations across different histological and molecular subtypes ofCMGTs, and toassess PI3K/Akt/mTOR pathway activity bymeasuring Akt and mTOR expression. Three carcinomas (C), three sarcomas (S),…

BACKGROUND: Elastofibroma dorsi is a rare, slow-growing, benign soft tissue tumor typically located under the scapula. Although elastofibroma dorsi is a benign lesion, it may cause symptoms such as pain and restriction of movement, and its mass-like appearance can lead to considerable patient anxiety. We aimed to pres…

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OBJECTIVES: Elastofibroma dorsi (ED) is a rare, benign, tumor-like soft-tissue lesion typically located in the subscapular region. Despite having a characteristic radiological appearance, clinical presentation and early postoperative course may vary from patient to patient. This study aimed to describe the clinical an…

Amaç: Extremite yumuşak doku sarkomlarının esas tedavisi geniş cerrahi eksizyon ve buna kombine edilen radyoterapi ve/veya kemoterapidir. Ekstremite yumuşak doku sarkomları negatif sınırlı cerrahi rezeksiyon ve adjuvan radyoterapiye rağmen lokal tekrarlama eğilimindedir. Çalışmada cerrahi kalitesinin değerlendirilmesi…

This study compared the effects of systemic Levofloxacin and Cephalexin on bone healing in a rat tibial fracture model. The subjects were divided into six groups (n=7 each): healthy control, fracture control, healthy Levofloxacin, healthy Cephalexin, fractured Levofloxacin, and fractured Cephalexin. In total, 42 Sprag…

In this case report, we present the clinical, radiological, and histopathological findings of a submandibular sialolipoma, a tumor rarely reported in the literature. Case ReportA 58-year-old female patient presented to our clinic with a complaint of swelling in the left submandibular region.She reported that the swell…

Cervical carcinosarcoma and leiomyosarcoma are rare and complex malignancies that pose diagnostic and treatment challenges. The rarity of these cancers complicates the development of standardized treatment protocols. This report details two cases of primary sarcomas of the cervix, exhibiting different histological fea…

Objective: The objective of this study was to investigate the relationship between intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) and dynamic contrast-enhanced MRI (DCE-MRI) parameters in soft tissue tumors (STTs). Methods: This retrospective study included patients with histopathologically confirm…

Objective: Tumor grade is critical for prognosis, metastatic risk, and treatment planning in soft tissue sarcomas (STSs). This study evaluated the role of quantitative dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) parameters and diffusion-weighted imaging (DWI) in predicting STS grade. Methods: Betwee…

Objective: In advanced-stage testicular cancer, postchemotherapy retroperitoneal lymph node dissection (RPLND) is performed to manage residual retroperitoneal masses. This study evaluated the histopathological features and their associations with primary tumor and clinical outcomes. Methods: Postchemotherapy RPLNDs pe…