Pain Mechanisms and Treatments

Erector spinae plane block in a patient with post-thoracotomy pain syndrome and intercostal neuralgia presenting with late-onset myoclonus: a case report 2026

Post-thoracotomy pain syndrome (PTPS) is a complex post-surgical chronic pain condition of the chest wall involving neuropathic, nociceptive, and nociplastic components, with intercostal neuralgia contributing in some cases. Intercostal neuralgia may occasionally present with motor manifestations, although such presen…

PROLOTHERAPY IN MYOFASCIAL PAIN SYNDROME 2026

No abstract yet.

Impact of pain subtypes on disability and quality of life in multiple sclerosis: Neuropathic pain demonstrates the strongest association 2026

No abstract yet.

Luteolin reduces sciatic nerve damage and modulates TRPV1 and TRPM2 expression in diabetic rats 2026

BACKGROUND: Hyperglycemia drives peripheral nerve damage through oxidative stress, inflammation, and apoptosis, yet the role of redox-sensitive ion channels in linking these processes remains poorly understood. OBJECTIVE: This study investigates the neuroprotective effects of luteolin (LUT) on streptozotocin (STZ)-ind…

Anti-Neuropathic Pain Activity of Epigallocatechin Gallate in an Experimental Diabetic Neuropathic Pain Via Inhibition of TRPV1 and iNOS 2026

Introduction: Diabetic neuropathic pain (DNP) is an important complication of diabetes.EGCG is known to have antioxidant, antiinflammatory, and antidiabetic effects.TRPV1 channel and iNOS are pain-related pathways.In this experimental DNP study, we examined the effects of EGCG on the sciatic nerve, focusing specifical…

Pressure pain threshold in combat and team sports athletes: An investigation of differences across anatomical regions 2026

The aim of this study was to examine the distribution of pressure pain threshold (PPT) across different anatomical regions in athletes engaged in combat and team sports and to determine whether these profiles differ according to sport type. A total of 72 athletes voluntarily participated in this cross-sectional study,…

MACHINE LEARNING-BASED OBJECTIVE ESTIMATION OF SPINAL PAIN INTENSITY ON THE VISUAL ANALOG SCALE 2026

The Visual Analog Scale (VAS) is widely used for assessing pain intensity in clinical practice; however, its subjective nature and limited scoring range may cause patient-related biases. This study aims to predict the error margin in pain severity estimation using the VAS through a machine learning-based model. Clinic…

Investigating the Analgesic Properties of MAO Inhibitors Moclobemide, Phenelzine, and Rasagiline in a Sciatic Nerve Ligation-Induced Neuropathic Pain Model 2026

Abstract Neuropathic pain, a complex condition resulting from somatosensory system damage, poses a significant clinical challenge due to the limited efficacy and side effects of current treatments. This study investigated the analgesic potential of three monoamine oxidase (MAO) inhibitors—moclobemide (MAO-A), phenelzi…

Otizm Spektrum Bozukluğunda Sitokin ve BDNF Düzeyleri 2026

No abstract yet.

Idebenone attenuates sciatic nerve ligation-induced neuropathic pain through modulating antioxidant and anti-inflammatory mechanisms in rats 2026

No abstract yet.

Idebenone Attenuates Sciatic Nerve Ligation–Induced Neuropathic Pain Through Modulating Antioxidant and Anti-Inflammatory Mechanisms in Rats 2026

No abstract yet.

Ağrı Araştırmalarında Elde Edilen İstatistiksel Bulgular: Türkiye ve Dünya Verileri 2026

Ağrı, bireyin fiziksel, psikolojik ve sosyal işlevselliğini etkileyen çok boyutlu bir deneyimdir ve günümüzde küresel hastalık yükü içinde önemli bir halk sağlığı sorunu olarak kabul edilmektedir. Bu bölümde, ağrı araştırmalarında sıklıkla kullanılan ölçüm araçları (VAS, NRS, MPQ, SF-MPQ, BPI) ile dünya ve Türkiye'ye…

Works

Academicians

Feedback