Substance Abuse Treatment and Outcomes

Aim: The identification of alcohol and substance use disorders is primarily based on clinical evaluation, and the lack of accessible objective markers remains a challenge. This study aimed to explore whether routine hemogram parameters, analyzed using multiclass machine learning models, could assist in differentiating…

This study analyzes the public relations policies countries employ to combat substance addiction. The research population consists of the countries listed in the World Drug Report. The sample includes Türkiye, the United States, Bangladesh, Australia, Spain, and South Africa, selected to represent diverse socioeconomi…

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Abstract Rationale Cannabis withdrawal contributes to relapse in individuals with cannabis use disorder, yet preclinical studies have largely focused on withdrawal induced by injected cannabinoids rather than inhaled cannabis, which remains the most common route in humans. The behavioural effects of chronic exposure t…

Substance use disorder (SUD) is a disease that affects not only the individual but also the family system in a multidimensional way. This chapter addresses the psychosocial impacts experienced by the families of individuals living with addiction, their help-seeking processes, and the dynamics of their participation in…

BACKGROUND: This study examined whether repeated incarceration among justice-involved male adolescents with substance use disorder (SUD) reflects not only a legal consequence but also a marker of a more severe clinical risk profile. It also evaluated the roles of addiction severity, family criminal history, psychologi…

Stigmatizing attitudes held by healthcare professionals toward individuals with alcohol and substance use disorders (ASUD) can hinder access to care and negatively affect treatment outcomes. Clinical experience may play a key role in shaping these attitudes. This cross-sectional study included 230 healthcare professio…

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Background: Cannabis use among university students has been increasingly linked to psychological distress; however, most evidence comes from Western contexts, and little is known about how cannabis use intersects with emotional functioning in non-Western settings. In Türkiye, where cannabis use remains illegal and hig…

This randomized controlled clinical trial aims to compare the effectiveness of Dialectical Behavior Therapy (DBT) and Motivational Interviewing (MI) in the treatment of Cannabis Use Disorder (CUD) among adults receiving outpatient care in Istanbul, Türkiye. Cannabis Use Disorder is defined according to DSM-5-TR diagno…

Abstract Background MicroRNAs are critical regulators of neuronal plasticity, synaptic signaling, and stress response, and their dysregulation has been implicated in substance use disorders. However, postmortem evidence on their involvement in Alcohol Use Disorder (AUD) remains limited. We aimed to investigate the exp…

Abstract Purpose of Review Gambling disorder is recognized as a behavioral addiction characterized by persistent and recurrent problematic gambling behavior that leads to clinically significant impairment or distress. Despite growing international research, comprehensive evidence on gambling disorder in Türkiye remain…