Article detail · 2018
Serum paraoxonase activity and total sialic acid in sheep with foot and mouth disease
- Year
- 2018
- DOI
- 10.21521/mw.6078
- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- YÖKSİS venue Medycyna Weterynaryjna
- Catalog match (ISSN) Medycyna Weterynaryjna
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
OpenAlex · English
The aim of this study was to investigate paraoxonase (PON1) activity and total sialic acid to be measured for the first time in sheep infected naturally with foot and mouth disease, and their relationships with oxidative stress. A total of 30 Awassi sheep (aged between 2–4), which were healthy and infected with the foot and mouth disease virus (FMDV) were used in the study. Concentrations of paraoxonase activity (PON1), which is an important antioxidant against oxidative stress, high density lipoprotein (HDL) and total sialic acid (TSA), which has a critical role for immune system and is one of the significant indicators of cellular degeneration, were measured in serum samples drawn from animals. The total oxidant capacity (TOC) and total antioxidant capacity (TAC) were evaluated to determine the oxidative balance. It was observed that serum PON1 (P<0.001) and HDL (P<0.01) concentrations were significantly lower compared to the control group. TSA concentration was higher in the infected group (P<0.001) compared to the healthy group. TOC was higher (P<0.001) and TAC was lower (P<0.01) in the infected group compared to the control group. Consequently, harmful effects of the infection of foot and mouth disease were shown as cause of oxidative cell damage and the high rate of sialic acid was produced depending on the degeneration during the infection. .
Topics
Citations
OpenAlex cited_by_count. Not a WoS or Scopus citation count; those sources have no separate column here.
6 citations
OpenAlex cited_by_count (cache / database)
6 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).
- Enfektif Hastalıklarda Oksidan ve Antioksidan Parametrelerin Rolü: Sistematik Bir Literatür Değerlendirmesi 2020
- Evaluation of Oxidative Stress Index and Some Biochemical Parameters in Neonatal Calves with Diarrhea 2021
- Evaluation of Oxidative Stress Index and Some Biochemical Parameters in Neonatal Calves with Diarrhea 2021
- Toksoplazmozisli Koyunlarda Oksidatif Stres ve Seruloplazmin Düzeylerinin Belirlenmesi 2020
- Determination of Oxidative Stress Index and Total Sialic Acid in Cattle Infested with Hypoderma spp. 2020
- Investigation of some acute phase proteins and antioxidant/oxidant system in infected sheep with bluetongue virus disease 2022