Solitary Orbital Plasmacytoma Associated with Chronic Hepatitis C: A Case Report

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PURPOSE: To report a rare case of solitary orbital plasmacytoma associated with chronic hepatitis C. METHODS: We have reviewed the case of a man who presented with soft tissue mass in the superolateral orbit. Biopsy demonstrated immunohistochemical positivity of plasma cells for lambda light chains and CD56. Systemic evaluation was negative for multiple myeloma, and the diagnosis of solitary orbital plasmacytoma was made. RESULTS: We comment on the rarity of the case according to the reviewed literature. CONCLUSIONS: Given the correlation between hepatitis C and other lymphoproliferative disorders, we conclude hepatitis C may also be associated with solitary plasmacytomas.