Article detail · 2018
Biofabrication of in situ Self Assembled 3D Cell Cultures in a Weightlessness Environment Generated using Magnetic Levitation
- Year
- 2018
- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- YÖKSİS venue Scientific Reports
- Catalog match (ISSN) Scientific Reports
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
OpenAlex · English
Magnetic levitation though negative magnetophoresis is a novel technology to simulate weightlessness and has recently found applications in material and biological sciences. Yet little is known about the ability of the magnetic levitation system to facilitate biofabrication of in situ three dimensional (3D) cellular structures. Here, we optimized a magnetic levitation though negative magnetophoresis protocol appropriate for long term levitated cell culture and developed an in situ 3D cellular assembly model with controlled cluster size and cellular pattern under simulated weightlessness. The developed strategy outlines a potential basis for the study of weightlessness on 3D living structures and with the opportunity for real-time imaging that is not possible with current ground-based simulated weightlessness techniques. The low-cost technique presented here may offer a wide range of biomedical applications in several research fields, including mechanobiology, drug discovery and developmental biology.
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Citations
OpenAlex cited_by_count. Not a WoS or Scopus citation count; those sources have no separate column here.
113 citations
OpenAlex cited_by_count (cache / database)
63 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).
- Magnetic Force-Based Microfluidic Techniques for Cellular and Tissue Bioengineering 2018
- Electromechanical RT-LAMP device for portable SARS-CoV-2 detection 2023
- Spheroid Engineering in Microfluidic Devices 2023
- Biomedical Applications of Magnetic Levitation 2021
- Label-free density-based detection of adipocytes of bone marrow origin using magnetic levitation 2019
- Label-free density-based detection of adipocytes of bone marrow origin using magnetic levitation 2019
- Magnetic Susceptibility-Based Protein Detection Using Magnetic Levitation 2020
- Bioprinting in Microgravity 2023
- HologLev: A Hybrid Magnetic Levitation Platform Integrated with Lensless Holographic Microscopy for Density-Based Cell Analysis 2021
- HologLev: A Hybrid Magnetic Levitation Platform Integrated with Lensless Holographic Microscopy for Density-Based Cell Analysis 2021