Article detail · 2008
Early and late effects of hyperbaric oxygen treatment on oxidative stress parameters in diabetic patients
Journal
Physiological Research- Year
- 2008
- Type
- article
Data source split
- YÖKSİS venue Physiological Research
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
OpenAlex · English
Exposure to hyperbaric oxygen leads to increased amount of reactive oxygen species (ROS) that are derived from various sources. After the discovery that ROS can function as signaling molecules, the idea of ROS being hazardous to biological tissues has been challenged. The aim of this study was to examine the changes in oxidative stress parameters in diabetics undergoing hyperbaric oxygen therapy (HBOT) due to foot ulcers. Twenty patients, who received HBOT for diabetic foot ulcers, were included in the study. Blood samples were taken before HBOT and 30 min after exit from the chamber, on the day of the first and the fifteenth HBOT sessions. They were used for the determinations of malondialdehyde (MDA), 8-isoprostane and advanced oxidation protein products (AOPPs). 8-Isoprostane and AOPP levels were not altered significantly after the first HBOT session, while both were increased on the fifteenth day (p<0.05). MDA was significantly increased only after the first HBOT session, and remained unchanged on the fifteenth day (within-day variations). Plasma AOPP levels were lowered significantly after fifteen consecutive HBOT sessions (between-day variations). Decreased AOPP levels suggest that increased oxygenation of tissues due to HBO therapy may activate some endogenous factors that prevent hazardous effects of the disease itself.
Topics
Citations
OpenAlex cited_by_count. Not a WoS or Scopus citation count; those sources have no separate column here.
39 citations
OpenAlex cited_by_count (cache / database)
18 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).
- The effects of hyperbaric oxygen therapy on blood brain barrier permeability in septic rats 2011
- The effects of hyperbaric oxygen therapy on blood brain barrier permeability in septic rats 2011
- The effects of hyperbaric oxygen therapy on blood brain barrier permeability in septic rats 2011
- Long-term exposure to repetitive hyperbaric oxygen results in cumulative oxidative stress in rat lung tissue 2011
- The effects of hyperbaric oxygen therapy on blood–brain barrier permeability in septic rats 2011
- The effects of hyperbaric oxygen therapy on blood brain barrier permeability in septic rats 2011
- The effects of hyperbaric oxygen therapy on blood brain barrier permeability in septic rats 2011
- The effects of hyperbaric air and hyperbaric oxygen on blood brain barrier integrity in rats 2013
- The effects of hyperbaric air and hyperbaric oxygen on blood brain barrier integrity in rats 2013
- The effects of hyperbaric air and hyperbaric oxygen on blood–brain barrier integrity in rats 2013