Article detail · 2004
CLINICAL FEATURES, EPIDEMIOLOGY, AND EFFICACY AND SAFETY OF INTRALESIONAL ANTIMONY TREATMENT OF CUTANEOUS LEISHMANIASIS: RECENT EXPERIENCE IN TURKEY
Journal
Journal of Parasitology- Year
- 2004
- DOI
- 10.1645/ge-185r
- Type
- article
Data source split
- YÖKSİS venue Journal of Parasitology
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
OpenAlex · English
A total of 1,030 patients, 40.2% men and 59.8% women, identified during the period of October 1998 to November 2002 as having cutaneous leishmaniasis (CL), were studied; 1,431 lesions were identified in the 1,030 patients. One lesion was present in 80.7% of the patients. The size of the lesions (longest axis) was 13.6 mm (standard, 12.1 mm; range 3-150 mm). Most of the lesions were of the papular type (51.2%), although several atypical clinical presentations of CL were observed. The duration of the disease ranged between 1 and 72 mo (mean duration, 10.8 mo). The clinical suspicion of CL was confirmed by the observation of amastigotes on lesion tissue samples stained by Giemsa. The test was positive in 851 of 1,030 patients (82.6%). Intralesional meglumine antimonate solution (85 mg Sb/ml, 0.2-1 ml, depending on the size of the lesion) weekly until complete cure or up to 20 wk was used for first-line therapy of 890 patients (86.4%). We found that this regimen of intralesional Sb has an efficacy of 97.2% with a low relapse rate of 3.9% and no serious adverse side effects.
Topics
Citations
OpenAlex cited_by_count. Not a WoS or Scopus citation count; those sources have no separate column here.
85 citations
OpenAlex cited_by_count (cache / database)
30 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).
- Cutaneous Leishmaniasis in Turkey 2012
- Cutaneous Leishmaniasis in Turkey 2012
- Clinical practice guidelines for the diagnosis and treatment of cutaneous leishmaniasis in Turkey 2018
- Clinical practice guidelines for the diagnosis and treatment of cutaneous leishmaniasis in Turkey 2018
- Clinical practice guidelines for the diagnosis and treatment of cutaneous leishmaniasis in Turkey 2018
- Clinical practice guidelines for the diagnosis and treatment of cutaneous leishmaniasis in Turkey 2018
- Clinical practice guidelines for the diagnosis and treatment of cutaneous leishmaniasis in Turkey 2018
- Clinical practice guidelines for the diagnosis and treatment of cutaneous leishmaniasis in Turkey 2018
- The current clinical and geographical situation of cutaneous leishmaniasis based on species identification in Turkey 2019
- The current clinical and geographical situation of cutaneous leishmaniasis based on species identification in Turkey 2019