Article detail · 2018
Prognostic value of thiol/disulphide homeostasis in predicting testicular ischaemia-reperfusion injury in rats
- Year
- 2018
- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- YÖKSİS venue Andrologia
- Catalog match (ISSN) Andrologia
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
OpenAlex · English
Testicular torsion is a surgical emergency and the testicular salvage rate through surgical detorsion ranges from 42% to 88%. However, it is not known to what extent spermatogenic function is preserved in these testes. The purpose of the study was to demonstrate the prognostic value of thiol/disulphide homeostasis in rats for testicular ischaemia and ischaemia-reperfusion injury during early and late stages. A total of 21 Wistar albino rats were randomly divided into three groups. The 4 and 8-hr T/D (torsion/detorsion) groups were subjected to left testicular torsion by twisting the testes by 720° counterclockwise direction. The 2 cc venous blood samples were also collected from the 4 and 8-hr T/D groups after 4 and 8 hr respectively. It was determined that the native thiol, total thiol and disulphide values of 4 and 8-hr T/D group before detorsion were significantly lower than those of the sham group (p: 0.006; p: 0.003; p: 0.003). In the 8-hr T/D group, there was a positive statistically significant relationship at an 88.3% level between Johnsen's score and total thiol values before detorsion (p: 0.008). Our study showed that thiol/disulphide homeostasis may be a haematologic parameter in predicting testicular ischaemia and histopathologic injury in the testes following ischaemia-reperfusion.
Topics
Citations
OpenAlex cited_by_count. Not a WoS or Scopus citation count; those sources have no separate column here.
11 citations
OpenAlex cited_by_count (cache / database)
7 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).
- Effects of platelet rich plasma on spermatogenesis and hormone production in an experimental testicular torsion model 2021
- What is the protective effect of krill oil on rat ovary against ischemia-reperfusion injury? 2019
- What is the protective effect of krill oil on rat ovary against ischemia-reperfusion injury? 2019
- What is the protective effect of krill oil on rat ovary against ischemia-reperfusion injury? 2019
- What is the protective effect of krill oil on rat ovary against ischemia-reperfusion injury? 2018
- The effect of intestinal ischemia on plasma thiol/disulphide homeostasis in an experimental study 2021
- Thiol-disulphide balance in infertility secondary to varicocele 2019