Article detail · 2011
Consensus recommendations for standard investigative workup: report of the International Myeloma Workshop Consensus Panel 3
- Year
- 2011
- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- YÖKSİS venue Blood
- Catalog match (ISSN) Blood
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
OpenAlex · English
A panel of members of the 2009 International Myeloma Workshop developed guidelines for standard investigative workup of patients with suspected multiple myeloma. Both serum and urine should be assessed for monoclonal protein. Measurement of monoclonal protein both by densitometer tracing and/by nephelometric quantitation is recommended, and immunofixation is required for confirmation. The serum-free light chain assay is recommended in all newly diagnosed patients with plasma cell dyscrasias. Bone marrow aspiration and/or biopsy along with demonstration of clonality of plasma cells are necessary. Serum β(2)-microglobulin, albumin, and lactate dehydrogenase are necessary for prognostic purposes. Standard metaphase cytogenetics and fluorescent in situ hybridization for 17p, t(4;14), and t(14;16) are recommended. The skeletal survey remains the standard method for imaging screening, but magnetic resonance imaging frequently provides valuable diagnostic and prognostic information. Most of these tests are repeated during follow-up or at relapse.
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Citations
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457 citations
OpenAlex cited_by_count (cache / database)
11 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).
- International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma 2014
- European Myeloma Network recommendations on the evaluation and treatment of newly diagnosed patients with multiple myeloma 2014
- Serum Free Light Chain Response After 2 Courses of Induction Chemotherapy Predicts Prognosis in Myeloma Patients 2015
- Clinical characteristics and treatments outcomes in elderly patients with multiple myeloma: A multicenter retrospective study 2017
- Clinical Characteristics and Treatments Outcomes in Elderly Patients with Multiple Myeloma: A Multicenter Retrospective Study 2017
- Clinical characteristics and treatments outcomes in elderly patients with multiple myeloma:A multicenter retrospective study 2017
- Clinical Characteristics and Treatments Outcomes in Elderly Patients with Multiple Myeloma: A Multicenter Retrospective Study 2017
- Rapid detection of serum free light chains by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry 2023
- Rapid detection of serum free light chains by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry 2023
- Clinical Presentation and Treatment Outcomes of a Rare Hematologic Malignancy, Solitary Plasmacytoma: Single Center Experience 2022