Article detail · 2016
Craniofacial Characteristics of Thalassemia Major Patients
Journal
The Eurasian Journal of MedicineISSN 1308-8734
The ISSN points to another catalog journal; the name is from the YÖKSİS record.
- Year
- 2016
- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- YÖKSİS venue The Eurasian Journal of Medicine
- Catalog match (ISSN) Eurasian Journal of Medicine
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
English (OpenAlex)
OBJECTIVE: Thalassemias major are the most common autosomal recessive disorders; they are characterized by anomalies in the synthesis of the beta chains of hemoglobin and are often associated with varying degrees of craniofacial anomalies. The purpose of this study was to evaluate the craniofacial dimensions of β-thalassemia patients and to identify differences by comparing them to those of a control group. MATERIALS AND METHODS: The study comprised 43 thalassemia major patients and 26 age- and sex- matched healthy control subjects. Anthropometric measurements were performed in six different craniofacial regions (head, face, nose, mouth, eyes, and ears); a total of 23 craniofacial variables were measured. RESULTS: Craniofacial measurements in the regions of the face, nose, lips and mouth, and ears in the thalassemia major patient group yielded statistically significant differences compared to those in the control group (p<0.05). However, no statistically significant differences were observed in the measurements of the head and eye regions. CONCLUSION: The study increased our understanding of the craniofacial anatomy of thalassemia major patients and enabled us to obtain quantitative results.
Topics
- Hemoglobinopathies and Related Disorders
- Cleft Lip and Palate Research
- Folate and B Vitamins Research
Primary topic Hemoglobinopathies and Related Disorders