Article detail · 2019
Thiolated plastoquinone analogs: Synthesis, characterization, and antimicrobial evaluation
- Year
- 2019
- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- YÖKSİS venue Journal of Molecular Structure
- Catalog match (ISSN) Journal of Molecular Structure
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
OpenAlex · English
Scorzonera L. (Asteraceae) species are widespread and utilised as traditional medicine and edible plant. A phytochemical study on ethyl acetate fraction obtained from the ethanol extract of Scorzonera hieraciifolia Hayek (an endemic species of Turkey) roots resulted in isolation of nine compounds; 5-O-feruloyl quinic acid methyl ester (1), 1,5-di-O-feruloylquinic acid (2), chlorogenic acid methyl ester (3), 3-O-caffeoylquinic acid methyl ester (4), 1,3-di-O-caffeoylquinic acid methyl ester (5), 3,5-di-O-caffeoylquinic acid methyl ester (6), 4,5-di-O-caffeoylquinic acid methyl ester (7), caffeic acid (8), 3-(4’-Hydroxyphenyl)-2-propenoic acid (4″-carboxyl)-phenyl ester (9). Structures of the compounds were determined using spectral methods. All substances were isolated for the first time from this species and compound 9 is new for the family Asteraceae. In vitro antioxidant, anti-inflammatory and antimicrobial activities of petroleum ether, chloroform, ethyl acetate and n-butanol fractions were evaluated. Ethyl acetate fraction showed the highest amount of total phenolic content and antioxidant capacity. No significant antimicrobial activity was determined against tested bacteria and fungi. COX inhibition test was employed for anti-inflammatory studies, all fractions showed low inhibitory effect on both COX-1 and COX-2 enzymes in comparison with indomethacin.
Topics
Citations
OpenAlex cited_by_count. Not a WoS or Scopus citation count; those sources have no separate column here.
37 citations
OpenAlex cited_by_count (cache / database)
27 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).
- A UHPLC-QTOF-MS screening provides new insights into the phytochemical composition and biological properties of six Consolida species from Turkey 2020
- Three new dihydroisocoumarin glycosides with antimicrobial activities from Scorzonera aucheriana 2021
- Three new dihydroisocoumarin glycosides with antimicrobial activities from Scorzonera aucheriana 2021
- Bioactive phenolic contents of Scorzonera ketzkhowelii Sosn. ex Grossh. (Asteraceae) with comprehensive in vitro and in silico studies 2025
- Bioactive phenolic contents of Scorzonera ketzkhowelii Sosn. ex Grossh. (Asteraceae) with comprehensive in vitro and in silico studies 2025
- Phenolic compounds and bioactivity of Scorzonera pygmaea Sibth. Sm. aerial parts: In vitro antioxidant, anti-inflammatory and antimicrobial activities 2020
- Phenolic compounds and bioactivity of Scorzonera pygmaea Sibth. Sm. aerial parts: In vitro antioxidant, anti-inflammatory and antimicrobial activities 2020
- Undescribed and known phenolic acid derivatives with significant antioxidant activity from the Scorzonera parviflora Jacq. roots 2025
- Undescribed and known phenolic acid derivatives with significant antioxidant activity from the Scorzonera parviflora Jacq. roots 2025
- Undescribed and known phenolic acid derivatives with significant antioxidant activity from the Scorzonera parviflora Jacq. roots 2025