Article detail · 2023
Preparation and characterization of latanoprost-loaded PVA nanofibers as an ocular drug delivery system for glaucoma treatment
- Year
- 2023
- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- YÖKSİS venue International Journal of Polymeric Materials and Polymeric Biomaterials
- Catalog match (ISSN) International Journal of Polymeric Materials and Polymeric Biomaterials
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
OpenAlex · English
In this study, latanoprost-loaded polyvinyl alcohol (PVA/LAT) nanofibers were developed as an ocular drug delivery system for glaucoma treatment. The nanofibers were constructed via electrospinning and crosslinked by glutaraldehyde. The characterization studies were conducted by scanning electron microscopy, Fourier Transform infrared spectroscopy, Brunauer, Emmett, and Teller analyses, water contact angle measurements, and also swelling and degradation studies. The PVA/LAT nanofibers crosslinked with 0.5% glutaraldehyde solution for 20 min had a cumulative release of 52% for 23 days. The results demonstrated that the PVA/LAT nanofibers have a usage potential as an ocular drug delivery system for glaucoma treatment.
Topics
Citations
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12 citations
OpenAlex cited_by_count (cache / database)
7 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).
- Preparation and Characterization of Amoxicillin-Loaded Polyvinyl Alcohol/Sodium Alginate Nanofibrous Mat: Drug Release Properties, Antibacterial Activity, and Cytotoxicity 2025
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- Preparation, Characterization, and Antimicrobial Activities of Ceragenins Incorporated Into Polyvinyl Alcohol/Gelatin/Sodium Alginate‐Based Hydrogels for Treatment of Burn Wounds 2025
- Preparation, Characterization, and Antimicrobial Activities of Ceragenins Incorporated Into Polyvinyl Alcohol/Gelatin/Sodium Alginate‐Based Hydrogels for Treatment of Burn Wounds 2025
- A New Lotus-Leaf-Inspired Beaded Nanofiber Strategy for the Development of Cryogel/Nanofiber Hybrid Structures 2024
- A New Lotus-Leaf-Inspired Beaded Nanofiber Strategy for the Development of Cryogel/Nanofiber Hybrid Structures 2024