Article detail · 2021
Investigation the Relationship of Autism Spectrum Disorder and FOXP2, GRIN2B, KATNAL2, GABRA4 Genes
Noropsikiyatri Arsivi-Archives of Neuropsychiatry
- Year
- 2021
- ISSN
1300-0667- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
English (OpenAlex)
INTRODUCTION: gene variants in the pathogenesis of autism spectrum disorder. METHOD: genes were screened by next generation sequencing analysis in 96 patients who diagnosed with autism spectrum disorder. RESULTS: gene. Twenty three of these 69 variants were novel that were not previously reported in the literature. CONCLUSION: genes. Identifying genetic risk factors that play a role in the etiopathogenesis of autism spectrum disorder will contribute significantly to understanding the molecular mechanisms of the disease and the development of new treatment strategies. In this context, comprehensive molecular genetic studies such as whole exome or whole genome sequencing are required with higher number of cases in different populations.
Topics
- Genetics and Neurodevelopmental Disorders
- Autism Spectrum Disorder Research
- CRISPR and Genetic Engineering
Primary topic Genetics and Neurodevelopmental Disorders