Article detail · 2025
Predictive power of hematological and biochemical biomarkers in diabetic retinopathy
- Year
- 2025
- ISSN
2602-3741- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
English (OpenAlex)
Abstract Background/Aims: Diabetic retinopathy (DR) is estimated to affect 27.0% of individuals with diabetes, resulting in approximately 0.4 million cases of blindness. Identifying novel biomarkers with predictive value could offer a promising approach to enhance the management of diabetic patients Therefore, this study aimed to investigate the efficacy of hematologic and biochemical biomarkers in DR subtypes. Methods: This retrospective comparative case study was conducted on 111 patients with diabetes mellitus (DM), divided into three equal groups: non-retinopathic diabetes mellitus (NRDM), non-proliferative diabetic retinopathy (NPDR), and proliferative diabetic retinopathy (PDR). The changes in the neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), eosinophil-monocyte ratio (EMR), monocyte-lymphocyte ratio (MLR), systemic immuno-inflammation index (SII), systemic inflammatory response index (SIRI), hematological, and biochemical parameters between the groups were investigated. Results: No significant difference was found in age, gender, or duration of DM between the groups. NLR, PLR, SII, SIRI, MLR, urea, and creatinine increased significantly with DR progression (P
Topics
- Inflammatory Biomarkers in Disease Prognosis
- Inflammation biomarkers and pathways
- Retinal Diseases and Treatments
Primary topic Inflammatory Biomarkers in Disease Prognosis