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Article detail · 2023

Recent Advances in the Anticancer Applications of Benzimidazole Derivatives

Journal

ChemistrySelect

ISSN 2365-6549

YÖKSİS OpenAlex SJR Q3 JCR Q3 Citations 28 Top 10% Percentile 93.0% FWCI 3.21
Year
2023
Type
article

Data source split

  • YÖKSİS YÖKSİS article record
  • YÖKSİS venue ChemistrySelect
  • Catalog match (ISSN) ChemistrySelect
  • OpenAlex OpenAlex enrichment (abstract, citations, topics)

Abstract

OpenAlex · English

Abstract Cancer, one of the most deadly diseases worldwide, is still a crucial challenge to human well‐being. Hence, the design and development of modern protocols to cure diverse kinds of cancer seem highly necessary. On the other hand, benzimidazole, as an essential pharmacophore, exhibits various biological and therapeutic potency. This compound is well‐known for its pharmaceutical features, including antifungal, antiviral, antibacterial, and anticancer activities. Therefore, benzimidazole derivatives have played an essential role due to their outstanding anticancer capability, apoptotic effect, and inhibitory potential. In recent decades, numerous anticancer drug types of research have been concentrated on finding new and practical strategies for employing benzimidazole‐based compounds. This review focuses on the latest advancements and methodologies for exploiting various benzimidazole‐bearing compounds for the treatment of varied sorts of cancer, considering the mechanism of their function against cancer cell lines.

Topics

Citations

OpenAlex cited_by_count. Not a WoS or Scopus citation count; those sources have no separate column here.

28 citations

OpenAlex cited_by_count (cache / database)

14 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).

  1. Recent advances in the application of heterogeneous catalysts for the synthesis of benzimidazole derivatives 2024 Citations 44 · OpenAlex
  2. Investigation of the cytotoxic activity, DFT calculation, and docking studies newly synthesized 1,3-disubstituted benzimidazolium chlorides on human liver cancer, lung cancer, and normal embryonic kidney cell lines 2024 Citations 14 · OpenAlex
  3. Investigation of the cytotoxic activity, DFT calculation, and docking studies newly synthesized 1,3-disubstituted benzimidazolium chlorides on human liver cancer, lung cancer, and normal embryonic kidney cell lines 2024 Citations 14 · OpenAlex
  4. Synthesis, Cytotoxic Activity, Docking and MD Simulation of N,N‐Disubstituted New Benzimidazolium Salts 2023 Citations 12 · OpenAlex
  5. Synthesis, Cytotoxic Activity, Docking and MD Simulation of N,N‐Disubstituted New Benzimidazolium Salts 2023 Citations 12 · OpenAlex
  6. Spectroscopic characterization, DFT calculations, antimicrobial activity, and molecular docking studies of 5-methoxy-1H-benzo[d]imidazole and its Ag(I) complex 2024 Citations 9 · OpenAlex
  7. Diaryl-substituted benzimidazole derivatives as antiproliferative agents: Design, synthesis, in vitro activity, and SAR analysis 2024 Citations 7 · OpenAlex
  8. Synthesis, Cytotoxic Activity, Antiquorum Sensing Effect, Docking and Md Simulation of Novel 1,3‐Disubstituted 2‐Mercapto‐1H‐Benzo[D]Imidazolium Chlorides 2025 Citations 4 · OpenAlex
  9. Synthesis, Cytotoxic Activity, Antiquorum Sensing Effect, Docking and Md Simulation of Novel 1,3‐Disubstituted 2‐Mercapto‐1H‐Benzo[D]Imidazolium Chlorides 2025 Citations 4 · OpenAlex
  10. Synthesis, Cytotoxic Activity, Antiquorum Sensing Effect, Docking and MD Simulation of Novel 1,3-Disubstituted 2-Mercapto-1H-benzo[d]imidazolium Chlorides 2025 Citations 4 · OpenAlex

Authors

  1. Mohammad Mavvaji
  2. SENEM AKKOÇ SÜLEYMAN DEMİREL ÜNİVERSİTESİ