Article detail · 2016
Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)
- Year
- 2016
- Type
- article
Data source split
- YÖKSİS YÖKSİS article record
- YÖKSİS venue World Journal of Emergency Surgery
- Catalog match (ISSN) World Journal of Emergency Surgery
- OpenAlex OpenAlex enrichment (abstract, citations, topics)
Abstract
OpenAlex · English
Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients. The cornerstones in the management of complicated IAIs are timely effective source control with appropriate antimicrobial therapy. Empiric antimicrobial therapy is important in the management of intra-abdominal infections and must be broad enough to cover all likely organisms because inappropriate initial antimicrobial therapy is associated with poor patient outcomes and the development of bacterial resistance. The overuse of antimicrobials is widely accepted as a major driver of some emerging infections (such as C. difficile), the selection of resistant pathogens in individual patients, and for the continued development of antimicrobial resistance globally. The growing emergence of multi-drug resistant organisms and the limited development of new agents available to counteract them have caused an impending crisis with alarming implications, especially with regards to Gram-negative bacteria. An international task force from 79 different countries has joined this project by sharing a document on the rational use of antimicrobials for patients with IAIs. The project has been termed AGORA (Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections). The authors hope that AGORA, involving many of the world's leading experts, can actively raise awareness in health workers and can improve prescribing behavior in treating IAIs.
Topics
Citations
OpenAlex cited_by_count. Not a WoS or Scopus citation count; those sources have no separate column here.
201 citations
OpenAlex cited_by_count (cache / database)
14 publications in the local catalog that cite this work (OpenAlex reference match; not the full global list).
- The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines for management of intra-abdominal infections 2017
- WSES/GAIS/SIS-E/WSIS/AAST global clinical pathways for patients with intra-abdominal infections 2021
- WSES/GAIS/SIS-E/WSIS/AAST global clinical pathways for patients with intra-abdominal infections 2021
- Ten golden rules for optimal antibiotic use in hospital settings: the WARNING call to action 2023
- The Global Alliance for Infections in Surgery: defining a model for antimicrobial stewardship-results from an international cross-sectional survey 2017
- The Global Alliance for Infections in Surgery: defining a model for antimicrobial stewardship—results from an international cross-sectional survey 2017
- A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway 2017
- A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway 2017
- Knowledge, awareness, and attitude towards infection prevention and management among surgeons: identifying the surgeon champion 2018
- It is time to define an organizational model for the prevention and management of infections along the surgical pathway: a worldwide cross-sectional survey 2022