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Article detail · 2018

Unio sp. primary cell culture potential in ecotoxicology research

Journal

Toxin Reviews

ISSN 1556-9543

YÖKSİS OpenAlex SJR Q3 JCR Q1 Citations 17 Percentile 55.1% FWCI 0.26
Year
2018
Type
article

Data source split

  • YÖKSİS YÖKSİS article record
  • YÖKSİS venue TOXIN REVIEWS
  • Catalog match (ISSN) Toxin Reviews
  • OpenAlex OpenAlex enrichment (abstract, citations, topics)

Abstract

OpenAlex · English

Primary tissue cultures from Unio pictorum were developed for utilization in ecotoxicology studies. Cytotoxic effects of selected plasticizers (BPA, DiNP, DiDP, DMP) were tested on digestive gland, gonad, gill and mantle cells. DiNP on gill and BPA on digestive gland were the highest and lowest cytotoxic compounds (IC50 0.111, 170.718 ppt). Mantle cells were the most suitable, reliable and easy to maintain cells; for toxicity assays. Unio primary cell culture provide valuable tool for testing/screening effects of xenobiotics in vitro, have potential for further development in terms of potential cryopreservation and stability comply with the 3 R principle.

Topics

Citations

OpenAlex cited_by_count. Not a WoS or Scopus citation count; those sources have no separate column here.

17 citations

OpenAlex cited_by_count (cache / database)

Authors

  1. BEGÜM YURDAKÖK DİKMEN ANKARA ÜNİVERSİTESİ
  2. PINAR ARSLAN ÇANKIRI KARATEKİN ÜNİVERSİTESİ
  3. ÖZGÜR KUZUKIRAN
  4. AYHAN FİLAZİ
  5. Figen Erkoç